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Oro-gastro-intestinal digestion of emulsified fat and how this digestion relates to colloidal stability and physiological responses

Primary Objective: To determine oral, gastric and duodenal lipid degradation of fat preloads .Secondary Objectives: To study how the oro-gastro-intestinal digestion of these fat preloads relates to: - Colloidal stability. For this we will monitor…

A multicenter randomized controlled trial of the effectiveness of pelvic physical therapy for children 5-17 years with functional constipation as SURPLUS to paediatric usual care

The purpose of this study is to investigate the effectiveness of pelvic physical therapy as a SURPLUS to the paediatric usual care in children (5-17 years) with functional constipation.Other research questions are: Does pelvic physiotherapy…

The effect of capsaicin and cinnamaldehyde on intestinal permeability, gallbladder motility and satiety

To obtain more information about the effects of capsaicin and cinnamaldehyde on the intestine, these substances will be infused directly in the duodenum. Hereafter, the permeability of the intestine, gallbladder motility and the effects on satiety…

A randomized controlled trial of physiotherapy in patients with fecal incontinence

This study is carried out to assess the effectiveness of rectal balloon training (RBT)combined with pelvic floor muscle training (PFMT) compared to pelvic floor muscle training alone in a population of patients with FI.

The effect of ethanol on intestinal permeability and integrity in healthy individuals

The study aims to investigate the effects of moderate ethanol drinking on the intestinal permeability and the tight junction complex. If there increase in the intestinal permeability, these effects will be investigated at molecular level.

Stimulation of the autonomic nervous system to improve postoperative recovery after colorectal surgery

To study the occurrence of postoperative ileus and the extend of the postoperative inflammatory response either systemic as well as locally in the bowel in patients receiving chewing gum before and after colorectal surgery.

A randomized clinical trial to evaluate the efficacy of polyethylene glycol vs psyllium fiber to prevent rebleeding in patients hospitalized with bleeding diverticular disease.

To evaluate the efficacy of laxatives (polyethylene glycol) versus supplementation of fibers on the incidence of rebleeding in patients hospitalized for colonic diverticular bleeding.

Effect of pneumodilatation in patients with prolonged dysphagia after antireflux surgery

To evaluate the effect of pneumodilatation (PD) on prolonged dysphagia after Toupet or Nissen fundoplication compared to sham dilatation.

The physiology of the anorectum, a pilot study

Our main objective is to investigate the mechanisms that regulate anorectal physiology.

Multicentre, Randomised, Controlled Trial of Gut-directed Hypnotherapy or Standard Medical Therapy in Children with Functional Nausea or Functional Dyspepsia

The aim of this study is to compare gut-directed hypnotherapy with standard medical treatment in children and adolescents with chronic idiopathic nausea or nausea due to functional dyspepsia. We will examine the effect of these treatments on…