400 results
Assess the feasibility of [18F]-DCFPyL PET/CT imaging to detect primary colon, gastric and pancreatic cancer.
To investigate the feasibility and safety of preoperative stereotactic radiotherapy of 4cm pancreas in patients undergoing pancreatoduodenectomy at high risk of developing postoperative pancreatic fistula (>25%).
The aim of the current study is to assess the feasibility, safety and efficacy of the Steam ablation System for eradication of short segment BE.
The primary objective of this study is to determine the accuracy of the application of stereotactic navigation combined with 3D MRI topography during oncologic resection for primary locally advanced rectal cancer in which the tumor is grown in or…
The OMEGA trial will primarily investigate if omentum preservation (partial omentectomy) during gastrectomy for gastric cancer is non-inferior to complete omentectomy in terms of three-year overall survival.
The study objective is to evaluate the efficiency of PerfusiX-Imaging compared to the current state of the art for perfusion measurements; indocyanine green fluorescence imaging. Also, feasibility and safety of PerfusiX-Imaging for perfusion…
Primary Objective: To further develop and evaluate a personalised patient-centred surveillance programme including a feedback platform for patients after curative treatment for CRC in terms of health-related quality of life (HRQoL).The goal is for…
The primary objective of the current protocol is the diagnostic value of a gastroscopy to detect gastric (pre)-neoplastic conditions in patients who need a colonoscopy as part of their clinical follow-up either after a positive screening test for…
Evaluation of IORT accuracy and effectiveness during rectal cancer surgery by determining the exact position and direction of the IORT beam through the use of an intra-operative electromagnetic image-guided navigation system.
We aim to confirm that Maastro endoluminal HDR contact brachytherapy boosting is feasible and may increase the chance of functional organ sparing of the rectum in patients with rectal cancer.
Primary• To evaluate the safety and tolerability of AMG 199 in adult subjects• To determine the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D) Secondary• To characterize the PK of AMG 199 • To evaluate preliminary anti-tumor…
The primary objective of the study is to determine the technical feasibility of ctDNA detection in small volumes of capillary blood. This will be investigated through determining the agreement between ctDNA measurements in venous (standard blood…
Since multiple dimensions (physical, emotional and cognitive) seem to be involved in the pathophysiology of fatigue, multidimensional approach to alleviate will probably have a synergistic effect. Previous studies supporting this assumption included…
The main purpose is to investigate the safety, pharmacokinetics and feasibility of ONM-100 as an intra-operative optical tracer to detect tumors and metastatic lymph nodes in solid cancers. Moreover, the study will investigate the optimal dose of…
This study is designed to assess the feasibility of NIRF with ICG during open or minimal invasive esophagectomy in order to assess the gastric conduit perfusion.
To evaluate the utility of the WATS system, as a potential substitute for the random sampling method that is currently recommended as an adjunct to targeted biopsy
Until recently, the field of anti-tumor immunology has focussed on the role of T lymphocytes. Recently, however, the group of prof. H. Spits and dr. T. Beaumont developed an in vitro methodology to grow human, monoclonal, B cell receptor positive…
The main objective of this study is to determine whether a single neoadjuvant gift of anti-EGFR mAb, administered 48 hours prior to local treatment of colorectal liver metastases, reduces the number of CTCs. Secondary endpoints are determination of…
The primary objective of this study is to investigate the association between changes of lean body mass and overall grade 2-4 toxicity during adjuvant chemotherapy in colon (or rectal) cancer patients.
This protocol is designed to determine the safety, tolerability, and efficacy of SGI-110 in combination with irinotecan in previously treated patients with metastatic colorectal cancer who progressed on irinotecan.