92 results
The aim is to investigate the feasibility of DBS from finger prick for measuring infliximab drug levels and ATIs compared with the results of venepuncture serum sample measurements. As a secondary objective, measurements of albumin and CRP will also…
To determine the correlation between concetrations of inflextra/ infliximab as measured using finger prick blood and lateral-flow assay and using venous blood and the standard sanquin ELISA.
to investigate the course of the pancreatic enzymes (serum amylase, serum lipase and urinary amylase) related to the course and stage of acute pancreatitis and thereby calculating the diagnostic accuracy of each pancreatic enzyme for acute…
To compare accumulation of liver fat (as measured using CAP) and liver fibrosis (as measured using fibroscan) between patients with quiescent and active inflammatory bowel disease
ObjectiveTo identify biomarkers for CAL in drain fluid and serum, in addition to RT-PCR for E. faecalis, that increase specificity and positive predictive value.
Determine if there are immunological or patient characteristics in UC patients that predict the endoscopic response on Vedolizumab treatment.
Primary objectives:to describe the composition of intestinal microbiota in the course of pediatric IBD-patients by IS-proto describe the composition of intestinal microbiota of apparently healthy children, aged 4-17 years, by IS-pro Secondary…
The main goal of this pilot study is to test feasibility of the present commercially available near-infrared fluorescence cholangiography (NIRFC) laparoscopic device during the laparoscopic cholecystectomy.
The overall objectives of this proposal are to develop two indices capable of measuring intestinal damage, and, separately, inflammatory disease activity in Pediatric Crohn's disease by means of Magnetic Resonance Imaging with Enterography…
Primary objective:Pharmacokinetics/-dynamics of 124I-F8IL10 Secondary objective:Dosimetric parameters of arthritic joints and internal organs.
The aim of our study is to assess 1) The influence of once daily versus twice daily use of 5-ASA medication on adherence 2) The influence of the use of apps on adherence in ulcerative colitis patients on 5-ASA
The overall aim of this study is to assess the feasibility of implementing MRE for use in evaluating fibrosis in patients with Crohn*s Disease (CD) in a multicenter setting.The primary objective for this study is to evaluate *gain of enhancement* as…
The aim of the study is to gain more insight in the course of intestinal oxygenation, urinary I-FABP concentration, and plasma Citrulline levels (as markers for intestinal damage and recovery) after NEC in relation to time to full enteral feeding…
The primary objective is the determination of faecal reference values of calprotectin, elastase and alpha-1-antitrypsin after RYGBP.
To study MRI of the small bowel and colon in determining disease activity in patients with Crohn*s disease.
Study the very long-term efficacy (regarding reflux control) of antireflux surgery in children with severe GERD.
The primary objective is to assess the feasibility and accuracy of dynamic contrast enhanced MRI in diagnosing UC or CD in children as compared to endoscopy and abdominal ultrasound.The secondary objective is to assess the feasibility of dynamic…
To study potential abnormal functioning of the bile salt-FXR-FGF19 axis in patients with clinically quiescent Crohn*s colitis.
The overall objective of this study is an improvement in (early) diagnosis of NEC and its life-threatening complications, thus to be able to detect children who are *at risk* for NEC and its complications as early as possible. To this end we will as…
In this study we will explore the examination with the second generation Pillcam capsule (PCCE 2) in patients with Crohn's disease. Crohn's patients with symptomps that need an endoscopy according to the treating physisian, will be asked…