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Safety and performance evaluation of the AutoLap system - a feasibility study

The main objectives of this study are to evaluate the safety and performance of the AutoLap system in the following laparoscopic procedures: hernia repair, cholecystectomy, right colectomy, Nissen fundoplication and sigmoidresection. The AutoLap…

Comparison of the effect of yoga and standard care on functional abdominal pain:
pain reduction and improvement of quality of life?
A randomized controlled trial

The aim of this study is to find a succesful treatment for functional abdominal pain in children and at the same time improve the quality of life of these children. A second aim is to reduce the hospital visits and with that the costs.

The effect of standard mindfulness based stress reduction (MBSR) on quality of life and symptom severity in patients with irritable bowel syndrome.

The research questions this study aims to answer are: What is the effect of a Mindfulness Based Stress Reduction (MBSR) training on IBS in terms of quality of life. It is hypothesised that participation in a MBSR-training will improve quality of…

Effect of domperidone and omeprazole in gastro-oesophageal reflux disease in infants between 0 and 2 years.

To measure the effect of domperidone and omeprazole on reflux-time, duration, and symptoms of GERD

Effect of Dientamoeba fragilis eradication on symptoms in children with abdominal pain

Effectiveness of treatment with clioquinol on parasitologic eradication is being studied as well as the clinical effectiveness of eradication in children with dientamoeba fragilis infection.

Treatment of dumping syndrome with Lanreotide Autogel

To determine the efficacy and tolerability of L-Autogel in patients with early or late dumping syndrome after gastric surgery.

Evaluation of the Performance of the Motus Cleansing System (MCS)

To evaluate the performance of MCS in cleansing a poorly prepared colon.

FREQUENCY AND SEVERITY OF HYPONATREMIA CAUSED BY PICOPREP BOWEL PREPARATION

Study the frequency and severity of hyponatremia caused by Picoprep bowel preparation.

Hypnotherapy through self-exercises in children with functional abdominal pain
in primary care

To determine the (cost)-effectiveness of home-based hypnotherapy by self-exercises added to usual care (UC) of general practitioners (GPs) compared with UC of GPs alone in children with FAP or IBS.

HELIOS-A: A Phase 3 Global, Randomized, Open-label Study to Evaluate the Efficacy and Safety of ALN-TTRSC02 in Patients with Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)

This study has been transitioned to CTIS with ID 2023-508365-33-00 check the CTIS register for the current data. To determine the efficacy of ALNTTRSC02 in patients with hATTR amyloidosis by evaluating the effect on neurologic impairment. To…

PHARMACOKINETICS OF APREPITANT, DEXAMETHASONE AND THEIR INTERACTION IN PATIENTS WITH CHEMOTHERAPY INDUCED NAUSEA AND VOMITING

Primary objective:The primary objective of this study is to define the differences in the interaction between oral dexamethasone and aprepitant and the interaction between iv dexamethasone and aprepitant.Secondary objective:The secondary objective…

Face-to-face versus online hypnotherapy for the treatment of Irritable Bowel Syndrome, according to a non-inferiority design. Three-armed randomized controlled trial. (FORTITUDE)

Primary objective:To compare the efficacy of online hypnotherapy versus face-to-face according to a non-inferiority design for the treatment of IBS.Hypothesis: Hypnotherapy delivered in the form of online exercises has non-inferior efficacy to face-…

The effect of Transcutaneous Vagal Nerve Stimulation on the processing of visceral pain signals: a High Resolution fMRI Study in Healthy Volunteers

Transcutaneous auricular vagal nerve stimulation (taVNS) has been recently shown to have analgesic potential in patients with chronic functional abdominal (visceral) pain. Functional abdominal pain, as commonly seen in conditions such as irritable…

Effect of an immune-supportive diet on gut permeability and allergic symptoms in children with peanut and/or nut allergy.

Therefore, the purpose of our study is to study, in peanut and nut allergic children:1. the relationship between gut permeability and threshold levels to peanut or nuts;2. the effect of an immune-supportive diet on gut permeability, coexisting…