28 results
The primary objective is to study the effect of paediatric pelvic physiotherapy in addition to conventional therapy on the number of patients with treatment success in children aged 4-17 years presenting in primary care with functional constipation…
The main objectives of this study are to evaluate the safety and performance of the AutoLap system in the following laparoscopic procedures: hernia repair, cholecystectomy, right colectomy, Nissen fundoplication and sigmoidresection. The AutoLap…
To investigate whether two newly developed, potato based LOPG drinks with a different osmolarity and volume taken before exercise, differently affect gastric distress after both a short and long term exercise, running performance, and the rate of…
To assess whether a combination of ciprofloxacin and adalimumab is more effective than adalimumab alone.
The aim of this study is to find a succesful treatment for chronic abdominal pain and small intestinal bacterial overgrowth in children and at the same time improve the quality of life of these children. A second aim is to reduce the hospital visits…
The aim of this study is to find a succesful treatment for functional abdominal pain in children and at the same time improve the quality of life of these children. A second aim is to reduce the hospital visits and with that the costs.
The research questions this study aims to answer are: What is the effect of a Mindfulness Based Stress Reduction (MBSR) training on IBS in terms of quality of life. It is hypothesised that participation in a MBSR-training will improve quality of…
To test whether probiotics, as adjuvant therapy, can reduce incidence and severity of migraine attacks by reducing intestinal permeability.
To measure the effect of domperidone and omeprazole on reflux-time, duration, and symptoms of GERD
Effectiveness of treatment with clioquinol on parasitologic eradication is being studied as well as the clinical effectiveness of eradication in children with dientamoeba fragilis infection.
To determine the efficacy and tolerability of L-Autogel in patients with early or late dumping syndrome after gastric surgery.
This monocenter randomized controlled trial aims to compare postoperative outcomes of a laparoscopic valvuloplasty with a Toupet fundoplication in patients with GERD with a maximum hiatal hernia of 3cm. In addition, an economic evaluation of the new…
Primary Objectives: To evaluate the overall bowel cleansing efficacy and the *Excellent plus Good* cleansing rate in the colon ascendens of a 1-day day before-only split-dosing regimen with NER1006 compared to a 1-day day before-only split-dosing…
To evaluate the performance of MCS in cleansing a poorly prepared colon.
To determine the (cost)-effectiveness of home-based hypnotherapy by self-exercises added to usual care (UC) of general practitioners (GPs) compared with UC of GPs alone in children with FAP or IBS.
This study has been transitioned to CTIS with ID 2023-508365-33-00 check the CTIS register for the current data. To determine the efficacy of ALNTTRSC02 in patients with hATTR amyloidosis by evaluating the effect on neurologic impairment. To…
Aim: To investigate the efficacy of nortriptyline in FD patients with a predicted CYP2D6 extensive metabolizer phenotype. Nortriptyline is a second generation TCA with significantly fewer anticholinergic side effects compared to the first generation…
To investigate the effect of a cows-milk-based formula supplemented with synbiotics from t=0 to t=21, t=42 and t=84 days after amoxicillin or amoxicillin/clavulanic acid treatment in toddlers aged 1, 2 and 3 years old on: - change in proportion of…
Primary objective:To compare the efficacy of online hypnotherapy versus face-to-face according to a non-inferiority design for the treatment of IBS.Hypothesis: Hypnotherapy delivered in the form of online exercises has non-inferior efficacy to face-…
Transcutaneous auricular vagal nerve stimulation (taVNS) has been recently shown to have analgesic potential in patients with chronic functional abdominal (visceral) pain. Functional abdominal pain, as commonly seen in conditions such as irritable…