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The effect of moderate alcohol consumption on a human in vivo model of low-grade systemic inflammation in young, normal-weight men

Primary objective: To explore whether prolonged moderate alcohol consumption affects in vivo cytokine response after a low dose of LPS in young, normal-weight men.Secondary objectives: To explore whether prolonged moderate alcohol consumption-…

Expression of factors involved in bile acid metabolism throughout the gastrointestinal tract
Amendement: Expression of HIF-1alpha protein in upper GI tractus

To obtain insights into the diverse nuclear receptors involved in the regulation of the bile acid cycle across the entire human gastrointestinal tract. Amendement:The aim of our study is to investigate the expression and amount of expression of HIF-…

Adherence of PREprocedural eating and drinking before a oesophasal-gastro-duodenoSCOpy to shorten prolonged fasting: A pilot study

Objective: to determine the feasibility of planned eating and drinking in preparation for oeshophagus-gastroduodenoscopy.

In vivo effects of amylase trypsin inhibitors from wheat in the human gut: proof of cause of non-coeliac wheat sensitivity in irritable bowel syndrome?

We aim to perform a proof-of-concept study to assess the effect of ATIs on the intestinal barrier and immune function in healthy volunteers. We hypothesise that the ATIs either directly affect the intestinal barrier function, or indirectly by…

Rationale: Gastric ultrasound is a quick and non-invasive tool to evaluate gastric content.
Emptying of gastric content can be affected after abdominal surgery leading to the inability of
tolerating oral foods. Gastric content can be assessed by gastric ultrasound and nurses were
recently trained to do so in healthy volunteers; however, feasibility of nurse-performed gastric
ultrasound after major abdominal surgery is not investigated yet.
Objective: To investigate the feasibility of nu

To investigate the feasibility of nurse-performed gastric ultrasound after major gastro-intestinal surgery.

Natural course of Pain following surgery through an Abdominal INcision: The Role of Adhesions and other factors in Chronification of abdominal pain

Primary objective is to elucidate the natural course of pain after abdominal surgery. Secondary objectives are assessment of risk factors for development of chronic pain after surgery, and comparison of adhesion formation between patient with and…