23 results
To investigate the feasibility and utility of indocyanine green fluorescence imaging for intraoperative perfusion assessment in patients undergoing gastro-intestinal surgery, primarily measured by the number of intraoperative changes in operation…
Primary ObjectiveTo assess the capability of the dPCR technique to predict the absence of disease relapses after imatinib discontinuation in CML patients with negative Q-RT-PCR results for longer than 18 months.Secondary Objectives• To estimate…
To identify what might be the cause of the occurrence of diarrhea during the use of angiogenesis inhibitors sunitinib and sorafenib in patients with a malignancy.
To make an efficacy evaluation of Gadolineum Ethoxybenzyl (Gd-EOB) DTPA-enhanced MR-imaging (Gadoxetic acid, Primovist, Bayer Schering Pharma, Berlin) and Respiratory Triggered Diffusion Weighted Imaging (DWI) for the detection and characterization…
The primary aim of the study is to compare the performance of the standard oblique-viewing US endoscope versus a prototype forward viewing ultrasonic endoscope for EUS-FNA of solid lesions of the GI tract and of adjacent organs.
Primary objective:Analyze the value of pneumoproteins, everolimus exposure, pulmonary function tests, distinct radiological patterns, baseline patient characteristics and the development of skin toxicity or oral mucositis for the prediction of the…
Tot evaluate the cognitive function of patients treated with sunitinib or sorafenib for metastatic renal cell cancer or a GIST, in order to get more insight in the prevalence, typeand etiology of cognitive dysfunctioning during treatment with…
The main objective of this study is to evaluate outcomes and resource needs of imaging and treatment following Primovist-enhanced MRI (PV-MRI) as com¬pared to ECCM-enhanced MRI (ECCM-MRI) and contrast-enhanced CT (CE-CT) in patients with a history…
Primary Objective: Sensitivity, specificity and positive predictive value (PPV) for the detection and characterization of focal liver lesions using Gd-EOB-DTPA contrast or DWI with TRONSecondary Objective(s): 1) Differences between sensitivity,…
To assess the influence of sunitinib and sorafenib on subjective and objective cognitive functioning in patients with metastatic renal cell cancer or a GIST, in order to get more insight in the prevalence, type and etiology of cognitive…
Uspio enhanced MRI (MRL) potentially has the ability to show all lymph nodes and hence provide information on metastasis in all nodes, this is in contrast with SLNB which only provides information on 1 (or a few) lymph node(s). With MRL metastases…
The primary objectives of our study are: - Determining the long-term predictive value of a positive HPV test for (pre)malignant cervical disease.- Determining the long-term protective value of a negative HPV test. - Determining the long-term…
To establish the preferred treatment of AIN to prevent the development of severe anal neoplasia (persistent AIN III or anal carcinoma) in HIV+ MSM and HIV+ woman.
The primary objective is to determine the positive and negative predictive value of an hrHPV test after treatment for the development of recurrent (cervical) disease on the long term.
Primary objectiveTo evaluate the efficacy of low dose intravenously lidocaine in comparison with placebo in terms of pain relief after the first oxaliplatin administration measured by a numeric rating scale (NRS 0-10).Secondary objectives1.…
The rationale of this study was to investigate the alteration of colonic motor patterns in the early postoperative stage and between patients with no or minor LARS-symptoms (LARS-score < 30) compared to patients experiencing major LARS…
CESM is a novel mammography technique that has been shown to be superior to conventional full-field digital mammography (FFDM). In a CESM exam, iodine based contrast agents, similar to those used in for example computed tomography (CT) exams, are…
With this prospective study, we aim to investigate the relationship between skeletal muscle mass and cisplatin plasma pharmacokinetics in HNSCC patients treated with conventional primary and postoperative CRT with cisplatin. It is designed to be a…
To investigate the effect of fluid infusion to prevent deterioration of kidney function due to pemetrexed, during treatment with carboplatin, pemetrexed and pembrolizumab in patients with non-squamous NSCLC. The primary objective is to reduce the…
Primary objectives:MoMaTEC2 aims to test the applicability of already identified and promising molecular biomarkers ER and PR, to improve risk stratification and individualisation of treatment for patients with EC.Secondary objectives:To perform a…