1025 results
Evaluation of the feasibility of sentinel node detection by PET-CT lymphoscintigraphy
1. To evaluate wether ABVS could replace HHUS in women <30 year with focal breast signs2. To evaluate the performance of ABVS in comparison to HHUS in patients with high suspicion of breast cancer3. To start a pilot study to compare ABVS with…
Primary objective:Analyze the value of pneumoproteins, everolimus exposure, pulmonary function tests, distinct radiological patterns, baseline patient characteristics and the development of skin toxicity or oral mucositis for the prediction of the…
The purpose of this study is to determine the thermal parameters by MRI scans at different time points during head-neck radiotherapy combined with hyperthermia treatment series.
The aim of the study is to create and optimize a DWI MRI scan protocol to assess thymic masses.
This project will first address the hypothesis that dual time-point 18F-FDG PET and DWI improve the discrimination between residual active tumor and inflammatory/necrotic changes after two cycles of R-CHOP in DLBCL / follicular lymphoma grade 3B ,…
The objectives of the current pilot study are: 1 to test the feasibility of the used vaginal probe and machine, settings and software that is currently used for the evaluation of prostates for uterine fibroids and to see if we need any modifications…
The goal of this study is to investigate the feasibility of the integration of an EMTS in a standard clinical EUS setting.
OBJECTIVE NOMETEC PART I: "Mapping the lymphatic drainage of the uterus: a feasibility study of the sentinel node procedure"Our aim is to find out which out of two injection methods with technetium labelled nanocolloid is the best to…
1. To construct a Dutch multicenter prospective biorepository for validation of biomarker and imaging products.2. To provide a Medical Technology Assessment (MTA) of newly developed biomarkers, contrast enhanced ultrasound and multimodality MR Iin…
The primary objective is to assess the contribution of HER2-PET to subsequent anti-HER2-therapy decisions. Secondary objectives are assessment of clinical value of HER2-PET for the referring clinician; correlation of HER2-PET with standard…
The primary objective of this study is to determine the sensitivity of the fluorescent tracer bevacizumab-IRDye800CW using a NIR fluorescence endoscope ans spectroscopy probe in identifying adenomatous polyps during surveillance endoscopy in…
• Determine the impact of variations in multi-parametric MRI on the prediction of tumor probability
A core part of the scientific efforts of ENS@T researchers bases on the establishment of a common registry and associated collection of biomaterials. Patients with adrenal tumours prospectively included in the ENS@T registry will be asked to provide…
To detect whether a web-based tailored information and support system improves patients* perception and satisfaction of received information. We hypothesize that after having received web-based tailored information and support patients feel more…
* To stratify cancer patients for participation in clinical trials.
The objective of this study is to examine the vestibular system in three dimensions. To achieve this goal three experiments are performed. The EyeSeeCam video-oculography is validated with the scleral search coils (international golden standard).…
Primary objective:To assess the safety, tolerability and pharmacokinetics of a single IV dosages of OTL-038. Selected doses of OTL-038 will be studied in the absence and presence of prophylactic treatment with the antihistamine clemastine to be…
Phase Ib:Estimate the maximum tolerated dose (MTD) and/or the recommended phase II dose (RP2D) of AEB071 and everolimus combination therapy inpatients with DLBCLPhase II:Assess the preliminary evidence for anti-tumor activity at R2PD for AEB071 and…
Phase Ib: Estimate the MTD and the RP2D of the combination of AEB071 and MEK162 in patients with metastatic uveal melanoma. And to assess the preliminary anti-tumor activity of the combination of AEB071 and MEK162. To characterize the PK profiels of…