77 results
The aim of the study is to create and optimize a DWI MRI scan protocol to assess thymic masses.
The goal of this study is to investigate the feasibility of the integration of an EMTS in a standard clinical EUS setting.
Primary objective is to analyse whether transnasal videolaryngoscopy in outpatient practice is more accurate in determination of the extend of the affected mucosa of laryngopharyngeal tumours compared to direct laryngoscopy under general anaesthesia…
(1) Investigate diagnostic performance (sensitivity) of HD bronchoscopy, with or without surface enhancement or tone enhancement in comparison to standard WLB for detecting abnormalities of the tracheobronchial tree. Furthermore we aim to…
To determine the toxicity of Zirconium-89 (Zr89) labelled Cetuximab in patient with stage IV cancer.
Primary Objective: The primary objective is to investigate whether EUS-TCB had an added value on EUS-FNA alone. Secondary Objective(s): The secondary objective is to study whether EUS-TCB does not have a higher complication rate than EUS-FNA alone.
To determine whether CT-PET virtual bronchoscopy guided TBNA (CT-PET-VB guided TBNA) is suitable for staging MLNs in patients with suspected LC.
The aim of this study is to design and test new intervention therapies on tumorcells or tumorsamples on there sensitivity for several new drugs. Last few years there are a lot of new drugs available for cancer and have to be tested on there…
To compare the feasibility of mutation analysis in samples obtained with EUS-FNA and EUS-TCB in patients with mediastinal lymph node metastasis in NSCLC. To compare EUS-TCB with EUS-FNA in diagnosing benign and malignant mediastinal disease.
Feasibility of PET probe guided extirpation of FDG-PET positive lymph nodes which are negative on other imaging modalities in head and neck cancer patients scheduled for primary irradiation.
To compare tumor [11C]erlotinib pharmacokinetics in NSCLC patients with and without erlotinib therapy. Also, to assess the relationship of venous sampling versus arterial, of tumor [11C]erlotinib uptake and blood flow with and without therapy, and…
Hypothesis: Fiducial markers implanted in mediastinal lymph nodes by EUS-FNA or EBUS will show inter and intra-fraction lymph node position variability on 4D-(CB) CT-scansObjective: To quantify respiratory induced mediastinal lymph node motion and…
To assess sorafenib pharmacokinetics and biodistribution, K-Ras mutational status, tumor uptake and tumor response in NSCLC patients.
To analyze the change in lymphatic mapping in HNSCC patients treated by primary radiation therapy on the primary tumor and neck.
To measure the test-retest reproducibility of tumor blood flow and associated measurements as measured with H2[15]O PET-CT in patients with non-small-cell lung cancer.
To analyze the value of lymphatic mapping in HNSCC patients with a previously treated neck.
To assess tumor reponse with FDG-PET-CT imaging early after start of concomitant chemo-radiotherapy in relation to cytological, histological and biological tumor characteristics. The ultimate goal is to reveal more insight in tumor reponse assesment…
To study the diagnostic accuracy of FDG PET and MRI as a function of time in the response monitoring and detection of residual lymph node metastases after non-surgical treatment of advanced head and neck cancer.
To determine if FDG PET/CT is performant enough with respect to detecting residual lymph node involvement after chemoradiation in order to omit planned neck dissections in patients with locally advanced potentially operable, N2 and N3 head and neck…
To investigate the dynamics of tumour hypoxia as assessed by 18F-FAZA PET/CT during and after chemoradiotherapy. To investigate the best strategy to deliver a boost dose to the hypoxic tumour areas. This strategy may be either a simultaneous boost (…