77 results
Feasibility of PET probe guided extirpation of FDG-PET positive lymph nodes which are negative on other imaging modalities in head and neck cancer patients scheduled for primary irradiation.
To determine whether CT-PET virtual bronchoscopy guided TBNA (CT-PET-VB guided TBNA) is suitable for staging MLNs in patients with suspected LC.
(1) Investigate diagnostic performance (sensitivity) of HD bronchoscopy, with or without surface enhancement or tone enhancement in comparison to standard WLB for detecting abnormalities of the tracheobronchial tree. Furthermore we aim to…
To compare the feasibility of mutation analysis in samples obtained with EUS-FNA and EUS-TCB in patients with mediastinal lymph node metastasis in NSCLC. To compare EUS-TCB with EUS-FNA in diagnosing benign and malignant mediastinal disease.
To evaluate the feasibility and potential of sentinel node biopsy in patients with (recurrences of) laryngeal carcinomas and clinically negative neck undergoing total laryngectomy and neck dissection.
The aim of this study is to design and test new intervention therapies on tumorcells or tumorsamples on there sensitivity for several new drugs. Last few years there are a lot of new drugs available for cancer and have to be tested on there…
Our goal is to study the effect of intravenous and oral contrast on the SUV in 18F-FDG PET-CT. The results will contribute to the adequate quantification of 18F-FDG-uptake in different clinical circumstances and the efficient use of combined PET-CT…
Comparison of micro arrays from biopsy material and surgical specimen for the 72 gene- prognostic profile of non-small cell lung cancer.
1. To study the effects of bevacizumab on [11C]docetaxel uptake by lung tumours.2. To study the early effects of bevacizumab on tumour blood flow.3. To study the relation between [11C]docetaxel uptake and blood flow in tumours after administration…
To evaluate the tumor targeting performance of the human radiolabeled antibody 124I-F16SIP.To investigate pharmacokinetics/-dynamics of 124I-F16SIP, and to assess its uptake in tumor and normal tissues as obtained from the surgical specimen.
Primary Objective: To study the tumour pharmacokinetics of [11C]erlotinib in NSCLC patients in vivo and relating uptake with EGFR mutations, obtained from tumour biopsies. Secondary Objective(s): 1. to define the test-retest reproducibility of [11C]…
To find correlations between tumour dimensions obtained by thresholds of uptake (SUV), metabolism (MRglu) or modelled thresholds (RTL) as measured during dynamic acquisition and anatomic (CT) and pathological data. Secondary objectives are the…
To investigate the dynamics of tumour hypoxia as assessed by 18F-FAZA PET/CT during and after chemoradiotherapy. To investigate the best strategy to deliver a boost dose to the hypoxic tumour areas. This strategy may be either a simultaneous boost (…
Primary objective is to analyse whether transnasal videolaryngoscopy in outpatient practice is more accurate in determination of the extend of the affected mucosa of laryngopharyngeal tumours compared to direct laryngoscopy under general anaesthesia…
The goal of this study is to investigate the feasibility of the integration of an EMTS in a standard clinical EUS setting.
To analyze the value of lymphatic mapping in HNSCC patients with a previously treated neck.
To study the diagnostic accuracy of FDG PET and MRI as a function of time in the response monitoring and detection of residual lymph node metastases after non-surgical treatment of advanced head and neck cancer.
To measure the test-retest reproducibility of tumor blood flow and associated measurements as measured with H2[15]O PET-CT in patients with non-small-cell lung cancer.
To analyze the change in lymphatic mapping in HNSCC patients treated by primary radiation therapy on the primary tumor and neck.
To assess tumor reponse with FDG-PET-CT imaging early after start of concomitant chemo-radiotherapy in relation to cytological, histological and biological tumor characteristics. The ultimate goal is to reveal more insight in tumor reponse assesment…