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Pilot study: Dystrophyc pathways in human hair follicles after chemotherapy with or without scalp cooling.

We will explore the influence of chemotherapy on hair follicles. Scalp cooling works, but not in every patient. When we understand the working mechanism of chemotherapy induced alopecia, we can possibly explain why scalp cooling works in one patient…

A phase III, multicenter, randomized, double-blind, placebo-controlled study to evaluate efficacy and safety of ribociclib with endocrine therapy as an adjuvant treatment in patients with hormone receptor-positive, HER2-negative, high risk early breast cancer

To compare invasive disease-free survival (iDFS) for ribociclib + ET versus placebo + ET in patients with HR-positive, HER2-negative, EBCwith high risk of recurrence.