20 results
To assess, based on a woman*s risk profile, mammographic density and age, the most cost-effective screening method, mammography or MRI, for women at high risk.
To establish biomarkers in nipple aspirate fluid, follow them in time and link them to breast cancer development at its earliest stage in women at high risk for breast cancer. Threshold values of biomarkers will be determined that point to a…
The aims of this project are to:1. Assess what percentage of breast cancer patients experience accelerated gain in fat mass, loss of muscle mass and muscle strength as induced during chemotherapy2. Assess whether changes in energy intake, protein…
Objective 1: To collect information on risk factors and biomarkers in a screening cohort, develop a tailor-made risk prediction model and, subsequently, model the impact of adapting breast cancer screening policy to populations at varying levels of…
We want to investigate wether a para-vertebral block contributes to a reduced postoperative pain and morphine consumption in patients with breast cancer after a unilateral mastectomy or lumpectomy. By doing this investigation we hope to clarify,…
The objective of this study is to investigate effects of different forms of patient information on chemotherapy side effects, in particular, assessing the severity and duration of the negative effects of information on chemotherapy-associated…
To compare dose homogeneity and heart and lung doses in supine and prone position. Furthermore, the reproducibility of prone position will be compared to standard supine position, and we aim to identify those patients who benefit most from prone…
To investigate that in mamma surgery, regional infiltration with ropivacaine 0,75% added to general anaesthesia causes less postoperative pain, nausea and vomiting compared to general anaesthesia alone.
·To compare the serological response to influenza vaccination in mamma carcinoma patients treated with FEC-containing, triweekly regimens at day 4 ( +/- 1 day) of the chemotherapy cyclus with the response to vaccination in otherwise healthy patients…
Riskreduction of developing breast carcinoma by means of better surgical techniques (removing all normal breast tissue).
- Assess the feasibility of the nipple aspiration procedure- Gain experience in methods and techniques of nipple aspiration - Identify factors that are associated with the fluid yielding status of nonlactating women- Assess the discomfort…
The aim of the here proposed study (BLOC-II) is to clarify whether cardiac function in survivors of BC should be monitored by GPs. We expect to clarify whether an unselected population of long-term BC survivors is at increased risk of developing…
The objectives of the BREHAB pilot study include both process and research objectives. Analysis of the process objectives will enable the feasibility of a larger RCT to be assessed. They focus on the feasibility of prehabilitation and rehabilitation…
To investigate the effects of a 5-day diet with 30% caloric and 70% protein restriction on cardiotoxicity induced by anthracycline treatment in women with triple negative or hormone receptor-positive breast cancer. The biomarker high-sensitivity…
Investigate the effect of hilotherapy on the severity of CIPN and nail toxicity, and its influence on treatment management and quality of life in patients with breast cancer during, and three and six months after treatment with Paclitaxel.
The primary objective of this study is to investigate the feasibility of a multimodal prehabilitation programme consisting of MIET during neoadjuvant intravenous chemotherapy infusion, HITT and strength training during the last six weeks prior to…
The OPTIMUM-study aims to gain insight into the optimal timing and method for promoting sustained adherence to lifestyle and body weight recommendations in PMBC survivors.The aim of the extra measurement during the second COVID-19 lockdown is to…
Primary objectives:- Investigate whether the activity of the bacterial enzyme β-glucuronidase and the abundance of β-glucuronidase-producing bacteria could be decreased by ingestion of 2 apples a day for a period of 6 weeks - Examine changes in gut…
The validation of microRNA expression for screening and prevention of breast cancer
To be able to assess the value of new markers, we first analyze these potential markers in nipple aspirate fluid and blood from healthy women. The main goal of this study is to evaluate the normal expression levels of microRNAs in NAF and blood to…