15 results
The primary objectives are:- to identify predictive factors for fatigue in cancer survivors on long-term sick leave. - to develop a prognostic instrument by which insurance physicians can assess future functional abilities, related to the work…
By means of this study we would like to answer the following questions:- Differs the humoral or cellular immune response after influenza vaccination between fatigued patients (with PCF or CFS) and non-fatigued patients?- Differs the humoral or…
To detect high-risk pathogenic mutations in germline DNA of children with childhood cancer that are suggestive of genetic predisposition, using NGS-based whole-exome sequencing, resulting in novel targets for future functional and translational…
To study the effect of early tumour development on brown adipose tissue activity
To investigate the state of the endothelial glycocalyx in cancer patients and determine the effect of chemotherapy on this layer.
In this project the expression, glycosylation and sialylation of mucins will be determined in tissue specimens of salivary gland tumors and in parallel, in the saliva of patients with a salivary gland tumor to determine whether altered mucin…
Primary objective: To monitor levels of microparticles in response to a gift of chemotherapy on short term and in response to multiple gifts of chemotherapy. Secondary objective 1: To compare microparticle levels measured in blood acquired via a…
1. Further delineation of four newly identified tumor predisposition syndromes in childhood cancer patients using 3D-analysis of facial morphology. 2. Identification of molecular genetic defects responsible for the tumor predisposition syndromes…
Our main objective is to determine the factors that increase susceptibility to IMC in order to find predictive biomarkers.
In 2004, a multidisciplinary team of clinicians and researchers in the UZ Leuven hospital started to collaborate on the rare problem of cancer during pregnancy. The collaboration between gynaecologists, pediatricians, hematologists, farmacologists,…
To define the immunohistopathological changes induced in the colon lamina propria by ICI therapy.
To obtain a fundamental understanding if and which chemotherapeutic agents used for treating cancer during pregnancy are associated with offspring (epi)genetic changes, potentially causing FGR and childhood/adult diseases later in life.
Primary objective: To assess the effect of ICI on progression of coronary non-calcified plaque volume and ICI-related cardiovascular events by measuring differences in plaque burden using repeated CCTA.Secondary objectives:- To evaluate the relation…
The aim of this study is to investigate the differences in organ-specific protein turnover rates by means of stable isotope labelled amino acid infusion in patients undergoing surgery. Primary objective:To compare protein synthesis rates, expressed…
Optimization of OE-MRI protocols and workflows to prepare for hypoxia mapping and quantification on an MR-linac