69 results
The primary objective of the study is to ascertain the feasibility and safety to image tumor angiogenesis in head- and neck cancer patients using Ga-68-DOTA-RGD2 PET/CT. Secondary objectives are to determine the pharmacokinetics and biodistribution…
The goal of this study is to be able to perform reliable measurements on AROM of neck and shoulders , exercise capacity, strength, MMO and functional mobility to evaluate the effectiveness rehabilitation programs in head and neck cancer survivors.
This trial will prospectively test the use of ultrasound imaging and pleural fluid analysis in improving the management of patients with malignant pleural effusion.Primary objective: Establish if the use of TUS before and during the first 24-72…
Primary objective- To evaluate the uptake of 68Ga-PSMA in locally advanced, recurrent and metastatic ACC or SDC by performing 68Ga-PSMA-PET/CT scans.Secondary objectives- To calculate the SUV tumor-to-background ratio and tumor-to-*healthy salivary…
a. Generate a tissuebank of fresh frozen tissue samples for biomarker research by establishing protocols and logistics for tissue collection, storage, annotation and retrieval. With additional goal the applicability in the standard clinical…
Cognitive behavior therapy (CBT) seems a promising intervention to reduce FCR. The SWORD study (Survivors* Worries of Recurrent Disease) will examine the efficacy and cost-effectiveness of individual CBT compared to treatment as usual (TAU) in…
Primary Objective: Evaluation of the potential of the incorporated SFR spectroscopy into the EUS-FNA procedure to discriminate benign and malignant pancreas tissue in vivo.Secondary Objective: To measure the wavelength dependent differences in…
To detect whether a web-based tailored information and support system improves patients* perception and satisfaction of received information. We hypothesize that after having received web-based tailored information and support patients feel more…
Determining the feasibility and diagnostic accuracy in terms of sensitivity and specificity of intraoperative detection of peritoneal carcinomatosis of colorectal origin by intraoperative fluorescence imaging using the VEGF-targeting optical imaging…
The objective of the study is to identify potential platelet-derived angiogenic and angiostatic tumorbiomarkers. Initially platelet proteomics will be used to detect potential tumormarkers. Subsequently, these potential tumorbiomarkers will be…
The aim of this prospective study is the prevention of progression of premalignant lesions to invasive head and neck cancer by modifying the out-patient follow up and patient management.
To measure the wavelength dependent differences in optical properties between normal and malignant breast tissue over a broad wavelength range (400-1000 nm).
Primary objectives:(1) Prevent progression of precursor lesions of the head and neck mucosa by treating selected lesions at risk for malignant outgrowth(2) Demonstrate that the detection of chromosomal instability (CIN) is indeed a powerful tool to…
Improving isolation and characterization technologies for CTC.
The overall aim of the proposed longitudinal cohort study is to expand our understanding of health-related work functioning among cancer survivors, who returned to work after first cancer diagnosis and treatment with curative intent during 18 months…
The objectuve of the study is to investigate the optimal geometry parameters and B-values by a acceptabel signal to nois ratio, for a diffusion sequention for MRI of the pancreas. It wil be investigate by a literature study and a practice study. The…
With this pilot study our aim is to lower the radiation dose. Therefore we will scan 5 patients at 100kV and 5 patients at 80kV and determine the resultant decrease in radiation dose, aiming at a dose comparable with a normal diagnostic CT scan with…
The main objective is to compare the clinical effectiveness of MRgUSBx versus MRgMRBx to provide evidence that MRgUSBx can partly replace MRgMRBx. Secondary objectives are: to determine the actual spatial targeting accuracy to further investigate if…
The primary objective is to determine if disease associated lesions in patients with VHLD can be visualized with 89Zr-bevacizumab PET scans. Secondary objectives are to explore if 89Zr-bevacizumab PET imaging can differentiate progressive from non-…
1) To diagnose occurrence and details (form, size, location) of cyst formation or other MRI abnormalities in patients with Ceramic-on-Polyethylene bearings; 2) To correlate these findings to the clinical status of the patient; .