19 results
To observe a decrease in number of definite and/or suspected pneumonia after prophylactic treatment with antibiotics during CRT in patients with LAHNC.To observe a decrease in the number of admissions in the hospital To observe a decrease in the…
Primary objectives: To compare the dose volume histograms (DVHs) of the planning target volume (PTV) in prone and supine position, with 3D conformal and intensity-modulated radiotherapy (IMRT) planning in patients who receive pelvic irradiation To…
Primary objectives:1) To determine whether concurrent ATII-antagonist treatment can prevent trastuzumab-related cardiotoxicity, defined as a decline in LVEF of more than 15% or a decrease to an absolute value <45%Secondary objectives:1) To…
The project primarily aims to study short (3 and 6 months) and long term (12 months) health related effects of the 'Kanker Nazorg Wijzer' on survivors' psychosocial distress and quality of life (QoL). Furthermore, process aspects of…
The proposed phase II study will test the hypothesis that preventive swallowing exercises (PSE) during treatment will reduce the incidence of swallowing dysfunction among patients with HNSCC treated with curatively intended (CH)-RT using SWIMRT. As…
To determine the efficacy (as measured by objective tumor response) of single agent everolimus in the treatment of advanced malignancies or high risk polyps of patients known with PJS .
The primary objective is the safety and feasibility of CEA/frameshift derived neopeptide loaded DC in patient with MSI-positive colorectal cancer and persons who are known to be carrier of a germline MMR-gene mutation with no signs of disease yet.…
The proposed study is part of a larger KWF program proposal: the Alpe d*HuZes Cancer Rehabilitation Research Program (A-CaRe) coordinated by the EMGO Institute. The aim of the study is to evaluate the short- and long-term effectiveness of a combined…
The objective of the study is to determine the clinical relevance of sparing the lymfdrainage of the upper extremitiy by using the ARM-procedure in patients with breast cancer. The purpose of the continuation of the feasibility study is to create a…
Primary Study Objectives:This study tries to objectives the potential benefit of prophylactic HBOT in terms of reducing / limiting the amount of dysphagia and / or xerostomia for tumors in the head and neck, specifically originating from the…
The primary objective of the study is to determine the rate of majorbleeding events in cancer subjects receiving extended treatment withdalteparin (> 6 months and up to 12 months) for prevention ofrecurrent symptomatic venous thromboembolism…
The objective of this study is to assess fatigue, physical activity, psychological wellbeing and quality of life in breast cancer patients during and shortly after adjuvant chemotherapy. We will study how often en how intense the symptoms occur. We…
The primary objective of this one-group pre-test post-test pilot study is to assess the feasibility of a home-based personalized prehabilitation program of approximately four weeks (usual care) in high-risk patients scheduled for elective colorectal…
The aim of this study is to investigate the amount of clinically relevant SRML (defined in this study as *5% muscle loss within one week measured by the cross sectional area (CSA) of the different muscles) in patients after major abdominal surgery…
The aim of this pilot is to get an impression of the feasibility and added value of administering deep sound waves to the body during (neo) adjuvant chemotherapy. In addition, we want to gain insight into whether or not complete completion of a…
This study has been transitioned to CTIS with ID 2024-517846-32-00 check the CTIS register for the current data. To evaluate the effect of prolonged duration of (fos)aprepitant prophylaxis on the prevention of delayed CINV (complete remission in the…
To determine the feasibility of at-home monitoring patients with oesophageal cancer during chemoradiotherapy.
The primary objective of this research is to gain insight into the short term (6 months) and long term (12 months) effects of the blended care protocol on cancer survivors* lifestyle behaviours. The secondary goal of this research is to gain insight…
The primary aim of this study is to investigate the effects on PA, sleep, stress, health and QoL of a tailored eHealth intervention for cancer patients when embedded in oncological care. Additional aims are to gain insight into the cost-…