88 results
The primary objective of the study is to ascertain the feasibility and safety to image tumor angiogenesis in head- and neck cancer patients using Ga-68-DOTA-RGD2 PET/CT. Secondary objectives are to determine the pharmacokinetics and biodistribution…
The aim of this study is to validate known, and identify novel allelic variants which may play a role in the risk of cisplatin-induced ototoxicity in a substantial international cohort of children diagnosed with cancer.
The goal of this study is to be able to perform reliable measurements on AROM of neck and shoulders , exercise capacity, strength, MMO and functional mobility to evaluate the effectiveness rehabilitation programs in head and neck cancer survivors.
This trial will prospectively test the use of ultrasound imaging and pleural fluid analysis in improving the management of patients with malignant pleural effusion.Primary objective: Establish if the use of TUS before and during the first 24-72…
The aim of this international field study is to test the scale structure, reliability, responsiveness to change and validity of the EORTC SHQ-C22 in patients with different cancer diagnoses, at different stages of disease, and with different…
Primary objective- To evaluate the uptake of 68Ga-PSMA in locally advanced, recurrent and metastatic ACC or SDC by performing 68Ga-PSMA-PET/CT scans.Secondary objectives- To calculate the SUV tumor-to-background ratio and tumor-to-*healthy salivary…
The primary objective of this study is to determine the impact of a diagnosis and type of treatment of cancer, ageing and their interaction on wellbeing of older cancer patients. Furthermore, we aim to determine the different psychosocial…
a. Generate a tissuebank of fresh frozen tissue samples for biomarker research by establishing protocols and logistics for tissue collection, storage, annotation and retrieval. With additional goal the applicability in the standard clinical…
Cognitive behavior therapy (CBT) seems a promising intervention to reduce FCR. The SWORD study (Survivors* Worries of Recurrent Disease) will examine the efficacy and cost-effectiveness of individual CBT compared to treatment as usual (TAU) in…
Primary Objective: Evaluation of the potential of the incorporated SFR spectroscopy into the EUS-FNA procedure to discriminate benign and malignant pancreas tissue in vivo.Secondary Objective: To measure the wavelength dependent differences in…
To detect whether a web-based tailored information and support system improves patients* perception and satisfaction of received information. We hypothesize that after having received web-based tailored information and support patients feel more…
Determining the feasibility and diagnostic accuracy in terms of sensitivity and specificity of intraoperative detection of peritoneal carcinomatosis of colorectal origin by intraoperative fluorescence imaging using the VEGF-targeting optical imaging…
The objective of the study is to identify potential platelet-derived angiogenic and angiostatic tumorbiomarkers. Initially platelet proteomics will be used to detect potential tumormarkers. Subsequently, these potential tumorbiomarkers will be…
The aim of this prospective study is the prevention of progression of premalignant lesions to invasive head and neck cancer by modifying the out-patient follow up and patient management.
Primary objective: To determine the feasibility, perceived usefulness, and patients' satisfaction regarding occupational rehabilitation during chemotherapy in a clinical setting, consisting of counseling by an occupational physician, and an…
To measure the wavelength dependent differences in optical properties between normal and malignant breast tissue over a broad wavelength range (400-1000 nm).
Primary objectives:(1) Prevent progression of precursor lesions of the head and neck mucosa by treating selected lesions at risk for malignant outgrowth(2) Demonstrate that the detection of chromosomal instability (CIN) is indeed a powerful tool to…
Improving isolation and characterization technologies for CTC.
The overall aim of the proposed longitudinal cohort study is to expand our understanding of health-related work functioning among cancer survivors, who returned to work after first cancer diagnosis and treatment with curative intent during 18 months…
The objectuve of the study is to investigate the optimal geometry parameters and B-values by a acceptabel signal to nois ratio, for a diffusion sequention for MRI of the pancreas. It wil be investigate by a literature study and a practice study. The…