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Cycling from hypothyroidism to hyperthyroidism during early treatment of differentiated thyroid carcinoma

Primary Objective: To compare the effects of hypothyroidism and hyperthyroidism on cardiac left ventricular function, as assessed by CMR, in subjects with differentiated thyroid cancer during their early treatment.Secondary Objective(s): To compare…

Gene polymorphisms and susceptibility to psychopathology in patients with metastatic carcinoid disease

In this study will be examined whether the polymorphisms of above mentioned genes are related to the occurrence and extent of psychiatric symptoms in patients suffering from carcinoid tumors. Since serotonin metabolism depends also on the tumor…

De-escalation of treatment for Papillary Thyroid Cancer followed by Active Surveillance - a pilot study

Primary Objective: The aim of this pilot study is to determine the willingness of patients to participate in a RCT regarding de-escalation of treatment of PTC and to observe adherence to this less aggressive approach. This will be accomplished by…

Efficacy of [18F]-2-fluoro-2-deoxy-D-glucose Positron Emission Tomography (FDG-PET) in Evaluation of Cytological indeterminate Thyroid nodules prior to Surgery: a multicentre cost-effectiveness study.

Main objective: To determine the impact of FDG-PET/CT on decreasing the fraction of patients with cytologically indeterminate thyroid nodules undergoing unbeneficial patient management.