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Determinants and mediating mechanisms of quality of life and disease-specific symptoms among thyroid cancer patients: the WaTCh study

Our main objective is to assess QoL and disease-specific symptoms over time. Our secondary objectives are to identify demographic, environmental, biological, physiological and personality characteristics of TC patients who are at high risk for poor…

Clinical pilot study to determine the feasibility of detecting pancreatic beta cells using Exendin-4-800CW targeting the glucagon-like peptide 1 receptor for future application of molecular fluorescence guided surgery in insulinoma patients (BETA-light)

The primary objective is to determine if accumulation of the fluorescent tracer Exendin-800CW can be detected to identify beta cells in patients undergoing pancreatic resection. Secondary objectives are to identify the dose of the NIR peptide (…

Treatment with Recombinant human Interleukin 1 receptor antagonist (Anakinra) in patients with Anaplastic Thyroid Cancer: a proof of concept study

To investigate the efficacy of treatment with human recombinant IL1Ra (rhIL1Ra, Anakinra) in patients with ATC in terms of improved health related quality of life (HRQoL), tumor progression and Overall Survival (OS). Secondary objectives: To…