10 results
To define and implement an uniform initial evaluation and stratification on adult patients with LCH, to uniform the treatment of adult patients with LCH and to improve treatment results with respect to survival, therapy response, prevention of…
The main purpose of this project is to investigate the conditions under which blood transfusions are successful in promoting microcirculatory circulation and oxygenation in anemic patients. In this project we wish to apply our state of the art…
To demonstrate the accuracy of FDG-PET for defining disease activity in relapsed MM patients in comparison to X-ray and somatostatin receptor scintigraph (SRS).
Objectives1. To assess the prevalence of sexual dysfunction in a Dutch cohort of female childhood cancer survivors.2. To assess the disease-associated risk factors for sexual dysfunction (type of treatment, age at treatment) in female childhood…
The expectation is that FDG-PET demonstrates or excludes infectious complications earlier than current practice, resulting in more efficient use of other diagnostic methods and therapy. Besides early detection and treatment of invasive fungal…
Objective of the studyThe present pilot study will be focused to define the sensitivity of SRS in MM patients and in patients with plasmacytoma. This in comparison to X-ray examination. In addition it will be investigated whether SRS can be used as…
- To determine the numbers of dividing cells focused whether hyperproliferation or hypoplasia can be determined.- To determine whether the progenotor or stem cell is different affected.- Can intrinsic defects of the CD34+ cells be demonstrated that…
The aim of this project is to validate 3 novel biomarkers (FDG PET/CT, WES and NGF). The utilization goal is to implement these biomarkers afterwards in clinical practice to rationalize treatment strategies. The primary objective is to validate the…
This study has been transitioned to CTIS with ID 2023-508101-24-00 check the CTIS register for the current data. The primary objective of the first randomized question (R1) open for allLBL patients (pts) of the core study cohort, is to evaluate…
To estimate the prothrombotic phenotype of patients with MM, on treatment with IMiD, using whole blood thrombin generation (WB-TG), platelet activation assays and PMC formation.