15 results
To identify and define characteristics of healthy lymph nodes and lymph nodes involved in different pulmonal diseases (lungcancer and sarcoidosis)
The primary objective of this project is to investigate whether 7T MRI spectroscopy biomarkers lactate and phospholipids can differentiate between aggressive and indolent lymphoma non-invasively. The secondary objective of this study is to assess…
Primary Objective:The primary objective of this study is to demonstrate that CNTO 328 in combination with BSC is superiorto BSC in terms of objective response (complete response [CR] + partial response [PR]) among subjectswith multicentric Castleman…
Primary objective:* To determine the safety, tolerability, dose-limiting toxicities (DLT), maximum acceptable dose (MAD) and maximum tolerated dose (MTD) of CHR-2845 when administered orally to patients with advanced or treatment refractory…
Primary Objective: The primary objective is to investigate whether EUS-TCB had an added value on EUS-FNA alone. Secondary Objective(s): The secondary objective is to study whether EUS-TCB does not have a higher complication rate than EUS-FNA alone.
The aims of this study are 1) to examine which magnetic field strength (1.0, 1.5, or 3.0 T) 2) in combination with which fat-suppression technique (STIR or SPIR/SPAIR) results in the best DWIBS images, 3) to detemine which respiration technique…
The aim of this study is to examine if WB-MRI can replace CT in staging of patients with a malignant lymphoma.
The aim of this study is to examine if WB-MRI can replace CT in staging of patients with a malignant lymphoma.
The objective of the study is to confirm that PCNSL is positive on 89Zr-rituximab PET imaging.
To assess the impact of access to feedback and access to an internet-based self-management intervention after primary treatment of lymphoma by increasing self-management and decreasing distress. We hypothesise that patients who have access to…
Primary Objective:Assess the safety and explore the biologically effective dose (BED) and/or the maximum tolerated dose (MTD) and/or the recommended Phase II dose (RP2D) of AZD4573 in patients with relapsed or refractory haematological…
This translational study focusses on the altered / improved immune response triggered by the addition of radiation to immune checkpoint blockade therapy. The study is investigative in nature.Main study parameters/endpoints:a) Alteration / increase…
To assess risk factors for cardiomyopathy and heart failure among lymphoma (HL and aggressive B-cell NHL) survivors, focusing on the independent and joint effects of doses of anthracycline-containing chemotherapy (doxorubicin) and rituximab as well…
The purpose of this study is to investigate how quickly and to what extend lenalidomide is absorbed and eliminated from the body (this is called pharmacokinetics). In this study the pharmacokinetics will be compared when lenalidomide is administered…
Primary Objective:To evaluate the efficacy of selinexor 60 mg in comparison to a minimally effective lower threshold level of ORR of 15% in patients with R/R DLBCL Secondary Objectives:* To determine DOR* To determine the disease control rate (DCR…