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Back-to-back high-definition white light endoscopy versus single-pass high-definition white light endoscopy and chromoendoscopy in IBD surveillance (HELIOS study)

Assessment of the detection of neoplastic lesions in patients with longstanding inflammatory bowel disease, using different endoscopic imaging techniques. Colonoscopy will be performed with either A) HDWLE, B) back-to-back HDWLE or C) CE.

Into the light: guided visualization of high-risk cancer precursor lesions

Research directionUntil now only the tumor has been part of the search for new molecular imaging targets. The associated microbial biofilm that is present on 89% of right-sided CRCs and conventional advanced adenomas (CAAs) has so far not been…

Discovery: Pentax* Computer-aided Detection to Improve Adenoma Detection in a Real-time Setting - The Discovery I Study

The primary objective of this study is to evaluate the feasibility of the Pentax CADe-system during colonoscopy procedures in terms of the polyp detection rate (PDR). We hypothesize that the use of the Pentax CADe-system is feasible and enables…

Linked Color Imaging versus high-definition white light endoscopy for the detection of polyps in patients with Lynch syndrome. An international, multicenter, parallel randomized controlled trial.

Fujifilm Linked Color Imaging versus high-definition white light endoscopy for the detection of polyps in patients with Lynch syndrome.

Diagnostic yield of screening colonoscopy in testicular cancer survivors treated with platinum-based chemotherapy

Primary objective of this multicenter study is to assess the diagnostic yield of colonoscopy surveillance in testicular cancer (TC) survivors treated with platinum-based chemotherapy (cisplatin). Furthermore, we will evaluate the molecular profile…

The European Polyp Surveillance study

1. To investigate the optimal time interval for colonoscopy surveillance in patients with low-risk and high-risk adenomas (EPoS I trial and EPoS II trial); 2. To evaluate the yield of surveillance in patients with clinically relevant serrated polyps…

Detection of upper GI tumour depth and demarcation by quantified fluorescence molecular endoscopy using systemic administration of ICG during endoscopic submucosal dissection

The primary objective is to evaluate the feasibility of ICG-enhanced near-infrared qFME to determine tumour demarcation and tumour depth in upper GI tumours (e.g. HGD or superficial oesophageal and/or gastric adenocarcinoma (T1)) during ESD.