110 results
- To assess the feasibility, safety and tolerability of cRGD-ZW800-1 for visualization of (neoadjuvantly treated) pancreatic carcinomas, perihilar or distal cholangiocarcinomas and if present associated metastatic lymph nodes and their distant…
Evaluating the feasibility of 18F-Fluciclatide PET/CT imaging of colorectal and pancreatic tumors.
Primary objective: to investigate how many patients with detectable ctDNA after surgery start with adjuvant chemotherapySecondary objective: to reduce recurrence rate by ctDNA based adjuvant chemotherapy (ACT) in stage II colon cancer (CC) patients…
- Primary: Determine safety and feasibility of immuno-OCT in vivo imaging with the tracer Bevacizumab-800CW. - Secondary: Validate the immuno-OCT endoscopy system based on:o Fluorescence molecular endoscopy;o Ex vivo fluorescence imaging; o Ex vivo…
The primary outcome parameters are identification rate of SLN(s) or lymph node metastases with bevacizumab-800CW, defined as the number of patients in which a SLN or lymph node metastasis was detected due to fluorescence during surgery and/or…
The main objective is to assess the central (cardiac function) and peripheral (skeletal muscle function) physiological adaptations in response to exercise prehabilitation.
Identification of patients with a high risk of progression of premalignant gastric lesions, in order to compose guidelines for surveillance and follow up.
Primary objectives:The primary objectives are to evaluate the feasibility of oral administration of bevacizumab-800CW and cetuximab-800CW for detection of neoplasia in BE patients compared to HD-WLE to shorten the qFME procedure and test whether…
This study has been transitioned to CTIS with ID 2024-510769-41-00 check the CTIS register for the current data. The main objective is to investigate the feasibility of a tumour-targeted fluorescent tracer SGM-101, combined with the use of the CE-…
To design, implement and test a multimodal prehabilitation program in order to lower the complication rate and improve recovery rate for patients undergoing colorectal surgery for colorectal cancer by enhancing functional capacity (cardiopulmonary…
The study consists of and endoscopic part (1) and an intraoperative part (2).1) Endoscopic part: to determine the feasibility and safety of molecular fluorescence endoscopy using the fluorescent tracer cetuximab-IRDye800CW targeting the epidermal…
To describe the accuracy of FAPI PET/CT in the detection of regional lymph node metastases in patients with colorectal cancer in comparison with standard diagnostic imaging and (in operated patients) histopathology, aiming to provide early evidence…
This project aims to unravel genetic and epigenetic alterations as well as characteristics of the tumor immune microenvironment that influence important biological processes in esophageal cancer and determine response or resistance to chemo-…
The primary objective is to study the feasibility of MRI in patients with esophageal tumors. We will study its effectiveness for visualization of the cranial and caudal tumor borders and identification of the involved lymph nodes.
The main objective is to compare overall survival of an active surveillance approach to that of standard surgery for patients with either squamous cell- or adenocarcinoma of the oesophagus or oesophago-gastric junction
Primary objective:The primary aim of this pilot study is to assess safety and feasibility of SLN identification using submucosal peritumoral ICG-nanocolloid injections.Secondary objectives:Secondary objectives are assessing detection rate and…
Translation of MR technique from research to clinical setting.
Assess the feasibility of [18F]-DCFPyL PET/CT imaging to detect primary colon, gastric and pancreatic cancer.
The primary objective of the current protocol is the diagnostic value of a gastroscopy to detect gastric (pre)-neoplastic conditions in patients who need a colonoscopy as part of their clinical follow-up either after a positive screening test for…
To evaluate the utility of the WATS system, as a potential substitute for the random sampling method that is currently recommended as an adjunct to targeted biopsy