110 results
To investigate the diagnostic accuracy and burden of MR colonography at 3.0 Tesla, using limited bowel preparation and CO2 for colonic distension.
Primary: Evaluate the ergonomics and function of the imaging system - the NIRF imaging system should not interfere with the standard esophagus resection and lymphadenectomy procedure by the surgeon while detection of indocyanine green (ICG) takes…
The aim of this study is to prospectively assess the occurrence of extra-intestinal manifestations in patients with MAP.
The objective for this study is to investigate different types of techniques and strategies, in order to optimize scan-parameters, image quality and patient acceptance in Magnetic Resonance Colonography.
To study the prevalence of anal intraepithelial neoplasia (AIN) by anal cytology and - histology and to determine the role of anal cytology and HPV testing in screening programmes on anal cancer in HIV-infected MSM.
To investigate what CTC iodine tagging-only bowel preparation gives a high image quality and readability of the CTC together with a high patient acceptance.
The aim of this study is to determine whether chromoendoscopy, including polypectomy of all detected lesions, reduces the development of colorectal neoplasia in Lynch syndrome patients at follow-up endoscopy.
To prospectively evaluate the feasibility and effectiveness of surveillance of individuals at high-risk for developing pancreatic cancer, in order to detect non-symptomatic (early) neoplastic lesions at a stage when curative resection is still…
Primary objective• To validate the potential of Vasovist®-enhanced MRI for accurate prediction of nodal status in patients with primary rectal cancer using histopathological examination after surgery as the SOR.Secondary objectives• To compare the…
The overall objective is to assess the effectiveness of treating patients with corticosteroids prior to surveillance in order to diminish the pitfall of active inflammation.
To compare the yield of autofluorescence guided targeted biopsy versus four-quadrant random biopsy in the evaluation of patients with known occult neoplastic lesions in Barrett*s Esophagus.
To investigate if there is a correlation between tumor perfusion and oxygenation, and downgrading of the tumor. This in order to better select those patient upfront, who will truely benifit from adjuvant radiation therapy.
To determine the additional value of NBI-ME to conventional endoscopy in the surveillance of patients with intestinal metaplasia and dysplasia, i.e. to evaluate whether the use of NBI-ME is superior to conventional endoscopy in the detection of…
Comparison of two new techniques for detection of small bowel pathology: MR enteroclysis and videocapsule enteroscopy with double-balloon enteroscopy with respect to diagnostic yield, accuracy of findings, and patient preference.
The primary objective of this study is to determine the sensitivity of the marker bevacizumab-IRDye800CW using innovative NIR fluorescence endoscopy (visualizing with wide-field endoscopy, measuring with MDSFR/SFF spectroscopy and optionally…
Aim of the present study is to investigate if a combination of a radioactive and fluorescent tracer can increase the sensitivity and specificity of the SLNM technique in colon and rectal cancer by utilizing the radioactive component for preoperative…
The objective of the MORE studies is to select and validate a biomarker profile predictive for the response to weekly paclitaxel and carboplatin chemotherapy concomitant with radiotherapy in patients with esophageal cancer.In the MORE-1 pilot study…
Primary objective: - To determine the feasibility of molecular fluorescence endoscopy using the fluorescent tracer EMI-137 in order to identify dysplasia and/or malignant lesions in patients with Barrett*s esophagus. - To evaluate the safety of EMI-…
Primary objectiveTo evaluate the efficacy of low dose intravenously lidocaine in comparison with placebo in terms of pain relief after the first oxaliplatin administration measured by a numeric rating scale (NRS 0-10).Secondary objectives1.…
The principal aim of this pilot study is to test whether ctDNA can be detected in peripheral blood of patients with an early CRC (i.e. pT1 CRC)