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Diagnostic Accuracy of an Electronic Nose as Compared to Combined Conventional CT-Scanning, Autofluorescense Scopy for the Detection of Early Endobronchial Squamous Cell Cancer after prior History of Head-and-neck Cancer or Lung Cancer

To evaluate the value of volatile organic compounds analysis by eNose in the early detection of second primaries or metastasis (and early lesions).

ENUMERATION AND CHARACTERISATION OF CIRCULATING TUMOR CELLS (CTC) IN PATIENTS WITH SOLID MALIGNANCIES

To enumerate and characterize CTC in patients with solid malignancies before and, if applicable, after initiation of systemic treatment in order to improve the insight in the pathogenesis of metastases, and in mechanisms conferring resistance…

Mapping the peritoneal immune system to identify novel immunomodulatory treatment options for diseases with peritoneal involvement.

AimThe MAPS study aims to unravel the immune composition of the human peritoneal cavity and the tumor immune environment in peritoneal metastasized gastric and colorectal cancer. The overarching aim is to find new targets for immunotherapy for this…

Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a multicentre, open-label, single-arm, phase II study (CRC-PIPAC)

To prospectively explore the feasibility safety, tolerability, preliminary efficacy, costs, and pharmacokinetic profile of repetitive ePIPAC-OX as a palliative monotherapy for isolated unresectable colorectal PM under controlled circumstances.