69 results
The main objective of the study was to prove the effectiveness of cryoablation in palliating pain and correlate the patients with a matched group of the Dutch bone metastasis study. The secondary objectives are to determine the accuracy of cryoprobe…
To compare the diagnostic performance (sensitivity and specificity) of 18F NaF PET/CT in comparising to 99mTc MDP bonescintigraphy in a cohort of patients with newly diagnosed prostate cancer at high risk of developing skeletal metastases and in…
To determine the effect of SRT on cognition and on quality of life of patients with one to 3 brain metastases, and to relate these outcome measures with radiological changes detected on MR imaging.
To evaluate the feasibility and prove the concept of sentinel node biopsy in patients with carcinoma of the parotid gland and scheduled for parotidectomy and elective neck dissection.
To study the value of whole body MRI in screening on distant metastases in HNSCC patients with high risk factors.
The aim of the present study is to measure the test-retest reproducibility of DW-MRI in healthy volunteers, in patients with colorectal liver metastases and in patients with malignant lung lesions in a multicenter setting.
Primary Objective: the primary objective of this study is to determine the feasibility of [18F]FDHT PET/CT for in vivo evaluation of bone metastases in prostate cancer. Active locations will be compared with those seen on conventional imaging (bone…
Radiolabeled bevacizumab as a tracer of VEGF expression in patients with colorectal liver metastases
Evaluation of tumor localization of In-111 labeled bevacizumab and possible correlation with VEGF expression in patients with colorectal liver metastases.
Evaluation and comparison of SNB and USgFNAC in the management of clinical negative neck in patients planned for transoral excision of oral and oropharyngeal squamous cell carcinoma.
To assess the influence of sentinel-node biopsy (SNB) on visualization of regional LNs using newly developed MRI techniques.
The main aim of this study is to determine the diagnostic accuracy of contrast-enhanced diffusion-weighted MRI (CE-DW-MRI) in the detection of liver metastases in patients with pancreatic cancer compared to a reference standard of histopathology and…
Optimisation of MRI research protocols including respiratory challenges with the RespirActTM.
The primary objective of this clinical performance study is to evaluate the effectiveness of the B7-H4 (A57.1) Assay in identifying B7-H4 positive (B7-H4 membrane staining at any intensity in ≥25% tumor cells) ovarian, endometrial, biliary tract,…
To assess the feasibility of simultaneous use of ICG and SGM-101 for intraoperative imaging of colorectal liver metastases.
Primary objective:To compose multifaceted predictive signatures for PD-1 or anti-PD-L1 antibody effects with relevant components of integrative omics (histology, immunohistochemistry, genomics, transcriptomics, proteomics, radiomics and molecular…
Primary Objectives1. To confirm superiority of Ferrotran®-enhanced MRI over unenhanced MRI in sensitivity to detect metastases in normal size pelvic lymph nodes in using histopathology after lymph node dissection as established reference method (…
1. To determine the feasibility of SGM-101 for intraoperative imaging of colorectal lung metastases - Concordance between fluorescent signal and tumor status of resected tissue2. To define the optimal dose of SGM-101 for intraoperative imaging of…
Primary objective:- To recruit patients to clinical intervention trials based on the mutational profiles of their individual cancer genome to improve treatment efficacy or intend to develop future predictors for response.Secondary objectives:- To…
Primary objective:- To evaluate pain and discomfort during and after injection of CM with varying temperatures (20° C and 37° C).- To evaluate the liver attenuation (HU) and image quality (IQ) using iodine injected with various temperatures (20°C…
The main objectives of this study is to evaluate if EGFR positive cervical lymph node metastasis can be detected non-invasively using the MSOT Acuity Echo with cetuximab-800CW as contrast agent in patients with oral squamous cell carcinoma.