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Minitub: Prospective registry of Sentinel Node (SN) positive melanoma patients with minimal SN tumor burden who undergo Completion Lymph Node Dissection (CLND) or Nodal Observation

With this prospective registry we aim to evaluate the outcome of patients with a T2-T3 primary melanoma and minimal SN tumor burden, treated by CLND or nodal observation:* The main objective is to determine if T2-T3 melanoma patients with minimal SN…

Detection of distant metastases in head and neck cancer patients by whole body FDG-PET and whole body MRI

To study the value of whole body MRI in screening on distant metastases in HNSCC patients with high risk factors.

Docetaxel versus Docetaxel and Lapatinib in recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN)
An open label multicenter randomized phase II study.
A study of the Dutch Head and Neck Cancer Group (DHNCG)
(NWHHT 08-02)

The primary objective of this study is to select the candidate treatment with the highest level of activity for subsequent phase III testing. Activity is defined as clinical benefit (CR,PR or stable disease) in patients with recurrent SCCHN not…

Microscopic and macroscopic liver tumor dimensions assessed with pathology and MRI studies to establish safety margins for stereotactic body radiation therapy: a pilot study.

- To measure the microscopic infiltration depth around colorectal liver metastases.- To correlate pathologic macroscopic/microscopic tumor dimensions with MR imaging findings.