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Cognitive Functioning And Health Related Quality Of Life In Retinoblastoma Survivors: The Role Of Cancer Treatment And Repeated Anesthesia

The specific aim of the current study is to investigate the impact of oncological treatment and multiple GA in Rb survivors and Rb risk carriers (8-35 years) on cognitive functioning, psychosocial functioning and HRQoL. Furthermore, psychological…

New strategies to detect cancers in carriers of mutations in RB1: blood tests based on tumor-educated platelets, or extracellular vesicles.

- The development of blood-based tests, either platelet or EV-based, for the detection of (the type of) tumors in RB1-mutation carriers.- Determine the non-cancerous baseline in adult RB1-mutation carriers (heritable-Rb-survivors).- Contribute to…

New Treatment Options for Metastatic Uveal Melanoma

The objectives of the study are the following: - To develop a treatment for uveal melanoma metastases. For this purpose, the following will be conducted:* To establish an European Biobank of (preferably matched) UM metastasis, primary tumor and…