24 results
Main study:We want to assess whether bleeding risk in women with uterine leiomyomas is associated with CK activity and attenuated platelet aggregation.Objective of pilot study:Firstly, to perform a feasibility pilot of CK/AK measurement in menstrual…
To investigate whether it is possible to manipulate perfusion in type 3 fibroids with MR-HIFU.
The objectives of the current pilot study are: 1 to test the feasibility of the used vaginal probe and machine, settings and software that is currently used for the evaluation of prostates for uterine fibroids and to see if we need any modifications…
To study the safety, toxicity and immunogenicity of a naked DNA vaccine encoding the shuffled HPV16 E7 gene product (TTFC-E7SH) in patients with HPV16+ VINIII lesions.
To compare vascular density and angiogenic factors in normal endometrium and endometrium covering submucous fibroids in patients with submucous fibroids.
The primary objective of this study is to evaluate feasibility of performing MR-HIFU treatment of uterine fibroids in a Philips Sonalleve MR-HIFU system equipped with a Direct Skin Cooling device. Secondary objective is evaluation of safety.
Treatment of endometrial hyperplasia by an IUD that contains progesteron is more effective and has less side-effects than the treatment with progesteron oral.
By investigating reasons for (non-)compliance with vaginal dilation in a sample of gynecological cancer patients receiving RT, we hope to identify facilitating and limiting factors relevant for the development of a sexual rehabilitation program.…
The primary objective of this study is to evaluate the technical success, feasibility and safety of hysteroscopic US guided cryomyolysis procedure.
To observate when necrosis in metastases of renal cell cancer is occurring.
Is hysteroscopic resection of submucous myomas under procedural sedation with propofol (PSA) in an outpatient setting a cost-effective alternative for hysteroscopic myomectomy performed under general anesthesia in the operation room?
The aim of this research is to test the efficacy and safety of a new microcatheter 2.8F Sequre for treatment of uterine fibroids and/or adenomyosis with a standard embolization technique and to demonstrate the added value of this catheter, namely to…
This study has been transitioned to CTIS with ID 2024-512602-26-00 check the CTIS register for the current data. Evaluate the (cost-) effectiveness of ulipristal in comparison with standard surgical treatment for symptomatic uterine fibroids,…
The objective of the present study is to evaluate the safety of Womed Leaf after hysteroscopic myomectomy and its potential efficacy in preventing IUA at second look hysteroscopy.
Optimize settings for contrast-enhanced ultrasound imaging of uterine disorders to obtain quantifiable images
This study aims to evaluate the impact of UAE on Quality of life (QOL) in comparison to hysterectomy in adenomyosis patients. A cost-effectiveness study will be part of the trial as well as a cohort hysterectomy group to clearify imaging and…
To identify molecular biomarker profiles that are associated with cervical tumorigenesis, and that can be used for development of an algorithm for detection of low grade CIN1, CIN2, CIN3 and cervical cancer. The algorithm should provide advice for a…
To evaluate the clinical utility of the NaPi2b (67) Assay for use in the detection of NaPi2b in formalin-fixed, paraffin-embedded (FFPE) serous ovarian carcinoma tissue to determine patient eligibility for treatment with XMT-1536.
* To study the safety of two naked DNA vaccines encoding sig-HELP-kdel and shuffled HPV16 E6 or E7 gene products (sig-HELP-E6SH/E7SH-kdel). * To study the systemic HPV-specific immune response of sig-HELP-E6SH/E7SH-kdel.
Objective of the phase II POP study:To determine the safety and preliminary anti-tumor activity of AZD1775 in combination with carboplatin in p53 mutated epithelial ovarian cancer in a 21 day schedule.Objectives of the additional safety and…