15 results
The primary objective for this trial is to assess the local cancer control achieved with FLA in patients with localized low to intermediate risk prostate cancer (Gleason 3+3, 3+4 or Gleason 4+3).Secondary objectives are to determine effectiveness of…
The primary objective of this study is to compare overall survival (OS) in patients with progressive PSMA-positive mCRPC who receive 177Lu-PSMA-617 in addition to best supportive/best standard of care versus patients treated with best supportive/…
Primary objectives- To determine the decrease in the CNS side effect fatigue* in frail (m)CRPC patients treated with a reduced dose of enzalutamide (120mg OD) compared to the standard dose of enzalutamide (160mg OD) after 6 weeks of…
The primary objective is efficacy of atezolizumab in advanced penile cancer patients measured by progression-free survival.
This study has been transitioned to CTIS with ID 2024-513867-19-00 check the CTIS register for the current data. Primary objective:Compare overall survival for subjects treated with docetaxel versus subjects treated with docetaxel plus raduim-…
The main objective is to assess if partial prostate brachytherapy will lead to less erectile dysfunction than whole gland prostate brachytherapy.Secondary objectives are:- To assess differences in urinary and rectal late effects between whole gland…
To investigate the technical feasibility of inserting a brachytherapy needle into the prostate to a defined tumour target point using a robotic device.
Main objective is to compare detection efficacy of 18F-PSMA-1007 PET-CT to 18F-Fluciclovine, in patients with early biochemical recurrence of prostate cancer.
To evaluate the incidence of grade * 3 neutropenia (measured at Day 7 and Day 14) and/or neutropenic complications (febrile neutropenia, neutropenic infection) with two schedules of cabazitaxel (bi-weekly versus tri-weekly) plus prednisone in…
To assess toxicity of MRI-guided focal salvage high-dose-rate brachytherapy (HDR-BT) in patients with locally recurrent prostate cancer. Secondary objectives are quality of life, biochemical disease free survival, dose restrictions, technical…
The objective of this trial is to compare standard treatment with radium-223-chloride (proven surivval benefit) with treatment with rhenium-188-HEDP, which is nowadays only used for pain palliation. This trial includes patients with metastatic…
We hypothesize that the follow-up and aftercare of prostate cancer in the Netherlands can be led by the GP. We hypothesize that GP-led recurrence detection programme leads to at least equal detection of recurrences as the current follow-up in…
Primary objective is to assess the prediction of tumour localisation, extraprostatic extension, metabolism and GS of 7T-MRI for PCa, based on anatomical, functional and metabolic imaging compared to whole-mount histopathology validation after…
Assessment of accuracy of sentinel node biopsy, defined as the false negative rate.
The aim of this study is to validate the effectiveness of the Stockholm3 test in the Netherlands setting with dutch patients.