48 results
The primary objective is to gain more insight in molecular alterations in CSU by performing a broad set of molecular analysis on tissue and blood ofpatients with carcinosarcoma of the uterus and find (bio)markers which can be linked to the clinical…
To determine the diagnostic performance and potential clinical benefit of DW-MRI as a staging tool to identify patients with advanced stage ovarian cancer who can benefit from cytoreductive surgery.
Primary: To determine whether the outcome of the RAD51 assay (HR proficient or HR deficient) correlates with objective response rate (RR) of olaparib, in patients with recurrent high grade epithelial ovarian cancer.Secondary:• Compare the…
Primary objective:To distinguish benign ovarium lesions from early cancer lesions, based upon their platelet RNA profile. Secondary objectives:* Evaluate the diagnostic accuracy of platelet RNA profiling in detecting early-stage ovarium cancer…
Primary* To confirm the efficacy of OTL38 in combination with fluorescent light to detect additional Folate Receptor-positive (FR+) ovarian cancer lesions not detected by palpation and visualization under normal light in patients with FR+ ovarian…
To determine the clinical effectiveness of adjuvant therapy given to all unstaged (no lymph node dissection) high risk stage 1 endometrial cancer, compared with only node positive (staged) cases as judged by fulllymph node dissection.
The primary objective of this study is to evaluate the additional value of biomarker HE4, as second step after the RMI score, in the triage of patients with an ovarian mass. We aim to improve the referral process to oncological centers. Secondary…
The primary objective of this study is to validate prospectively that testing for the DNA methylation status of some tumor suppressor genes predicts (non-)regression of a CIN2/3 lesion, and therefore can lead to prevention of overtreatment.