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2 results

Desmoid tumors in familial adenomatous polyposis; assessment of predictive markers.

Approved WMORecruitment stopped

The aim of our project is to develop a test that identifies FAP patients with a high risk to develop desmoids. In a recent study, a so-called wound-response gene expression signature was developed on the basis of serum stimulation of fibroblasts in…

A Phase 2, Open-Label, Adaptive, Dose-Ranging Study with Long-Term Extension to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetics of Intra-articular AMB-05X Injections in Subjects with Tenosynovial Giant Cell Tumor

Approved WMOCompleted

This study has been transitioned to CTIS with ID 2023-507328-22-00 check the CTIS register for the current data. The objectives of this study are to evaluate the safety, efficacy, pharmacokinetics (PK), and pharmacodynamics of intra-articular (IA)…