14 results
The purpose of the proposed project is to evaluate the immediate and long-term effects of cognitive rehabilitation in a prospective randomized trial on neuropsychological test performance and self-reported cognitive symptoms, psychological symptoms…
The primary objective of the study is to confirm that the addition of rindopepimut?GM-CSF to adjuvant temozolomide improves overall survival in patients with newly diagnosed EGFRvIII positive glioblastoma who have undergone gross-total resection.
The objective of this pilot randomized controlled trial (RCT) is to assess the feasibility and to determine the effect size of a physical activity/exercise program in improving objective cognitive functioning and reducing self-reported cognitive…
The primary objective of this study is to compare the overall survival (OS) distributions between LY2157299 monohydrate plus lomustine therapy with lomustine plus placebo therapy (control arm), in patients who have relapsed or have progressive GB…
The aim of this study is to investigate the efficacy of neurofeedback to improve attention and memory in children that have been treated for a brain tumour. If the neurofeedback proves to be effective, we will strive to implement this training for…
(1) investigating the influence of modafinil on fatigue, cognitive functioning, and quality of life of LGG patients, (2) assessing the correlation between (changes in) fatigue, cognition, and quality of life on the one hand, and functional…
Primary ObjectiveTo investigate whether ultrasound guided tumor resection succeeds gross total resection significantly more frequently, when compared with the conventional non-ultrasound guided tumor resection.Secondary Objective(s)To investigate…
The proposed study aims to examine the efficacy and process of an individualized (vs. standardized), comprehensive and family-centered neuropsychological intervention for pediatric brain tumor patients experiencing neuropsychological problems. The…
To investigate if resection with a margin, that is significantly beyond the radiological contrast enhancement, improves overall survival in selected patients with glioblastoma.
To investigate the effect of a three-week treatment with cannabidiol (CBD) on anxiety in patients with a primary brain tumor that have no active oncological treatment. Depression, fatigue and general quality of life are secondary outcome measures.…
To investigate the feasibility of a combination therapy (consisting of individualized rTMS and cognitive strategy training) and study measurements in patients with a primary brain tumor during stable disease. The study is considered feasible when 80…
This study has been transitioned to CTIS with ID 2024-512961-15-00 check the CTIS register for the current data. Primary:• The primary objective of the study is to demonstrate the efficacy of vorasidenib based on radiographic progression-free…
To determine whether the addition of ABT-414 to concomitant radiotherapy and temozolomide prolongs overall survival (OS) in subjects with newly diagnosed GBM harboring EGFR amplification.
Primary Objective* To determine the OS of subjects treated with ICT-107 and standard of care (RT and TMZ) vs. placebo control and standard of care (RT and TMZ) :Secondary Objectives* To determine the OS of subjects with unmethylated MGMT tumors…