10 results
The primary goal is to compare functional (language) areas in the brain found by preoperative fMRI, to those found during intraoperative ESM (electrical stimulation mapping) and fUS (functional ultrasound) during awake craniotomies, to see whether…
Firstly, to assess the ability of fUS to discriminate between functional and non-functional spinal cord areas using electrical stimulation paradigms during spinal cord tumor removal surgery. Secondly, to assess the ability of fUS to discriminate…
The primary objective is to develop and clinically validate a fast multi-parametric MRI acquisition technique, for non-invasive and comprehensive characterization of the tumor*s vascularization, *vascular signature mapping*, at 3 Tesla (3T) and 7…
Conducting research into the role of CSF and blood parameters of patients with CNS lymphoma, focused on improving the diagnostics, identification of biomarkers ('liquid biopsy'), and evaluation of therapy effect.
This study has been transitioned to CTIS with ID 2024-510578-25-00 check the CTIS register for the current data. Primary objectives:- To evaluate whether the outcome in children, young people and adults with HR-MB is improved over standard therapy i…
We will investigate (1) whether broadband power can be measured repeatedly and accurately within this patient population with limited variation in case of stable disease, (2) whether meaningful changes in broadband power in the case of real…
To investigate the effect of a three-week treatment with cannabidiol (CBD) on anxiety in patients with a primary brain tumor that have no active oncological treatment. Depression, fatigue and general quality of life are secondary outcome measures.…
Brain tumors: Characterize and quantify changes in immune parameters during disease in patients with a CNS malignancyAML: Characterize and quantify changes in immune parameters and immunotherapeutic targets during disease in pediatric patients with…
This study has been transitioned to CTIS with ID 2024-510691-20-00 check the CTIS register for the current data. The primary objective of Arm 1 is to evaluate the overall response rate (ORR) as determined by an independent radiology review committee…
The primary objective of this clinical pilot study is to explore the feasibility of Flatpanel Detector - Parenchymal Blood Volume (FD-PBV) imaging in patients with intracranial meningiomas during neurosurgery in the Hybrid-OR. Image quality, added…