125 results
Answering the question if there are any associations between hormonal status in adolescence on the one hand, and immunological reactivity and pharmacodynamics on the other hand; and if such associations can explain the more rapid deterioration of…
The main objective of this study is to assess whether ICD therapy in dialysis patients reduces sudden (arrhythmogenic) cardiac death. The first secondary end point is to compare total mortality death between the two groups. An other is to evaluate…
to determine if there is an alternative mechanism for urine acidification in men in response to NH4Cl other than that through ENaC
Primary Objective: • To compare urinary concentrating capacity in ADPKD patients with healthy subjects and patient with IgA- or membranous glumerulopathy.Secondary Objectives:• To compare urinary concentrating capacity in ADPKD patients with an eGFR…
To study the extent of impaired urinary concentrating ability in hypothyroidism as well as the pathophysiological mechanisms involved before and after adequate treatment.
The objectives of this study are to determine the prevalence of dRTA, osteoporosis and nephrolithiasis in patients with SS. We also try to elucidate the mechanism which is responsible for developing dRTA in patients with SS. The role of auto…
The overall aim of our study is to evaluate the management of suspected uncomplicated UTI in women presenting in primary care through use of a novel point of care test (POCT, Flexicult). This study is being carried out in 4 European networks: Wales…
To detect the differences in the length of the urethra in healthy volunteers and in men after laparoscopic radical prostatectomy.To detect the degree of erectiel dysfunction before and after laparoscopic radical prostatectomy.To detect the cause of…
The overall aim of this study is to evaluate the use of the thrombin generation test in patients with CKD, including haemodialysis-dependent patients.
To elucidate the molecular mechanisms underlying renal disease that lead to chronic kidney disease. To validate pathogenic variations in functional in vivo models.
The objective of the study is the confirmation or enervation of our hypothesis, i.e. that a situation is present in PD patients with normal peritoneal transport characteristics, whereby diffusion through the peritoneal membrane is retarded by PBR…
to study the effect of everolimus (vs. mycophenolate) on dyslipidemia, ectopic fat accumulation, and cardiovascular function against a common calcineurin inhibitor (CNI) background.
To assess renal sympathetic reinnervation in the kidney allograft by 123-I-MIBG scintigraphy.
The goal of the study is to investigate the difference between heart rate variability in patients with overactive bladder and patients with stress incontinence without overactive bladder, and also the difference in heart rate variability with empty…
The objective of this pilot study is to investigate the association between hemodialysis-associated changes in tryptophan levels and changes in symptoms of depression and fatigue, and the temporal dynamics between depression and fatigue.
1. to study the effect of spironolacton and triamterene on blood pressure in anuric hemodialysis patients.2. to study the effect of treatment on body weight, serum elektrolytes, 24-hours sodium excretion, plasma aldosterone and renin concentrations…
- To evaluate the demographic, clinical and genetic characteristics of all known patients with a diagnosis of cystinuria and cystine nephrolithiasis in the Netherlands.- To evaluate the relationship between genotype and phenotype of all known…
First, to determine the extent to which microcirculatory perfusion defects occur during clinical kidney transplantation. Second, to study the relationship between these events and kidney function, inflammation and renal cellular injury. Third, to…
The primary aim of this research project is to investigate the prevalence and bother of OAB before and after POP repair surgery and to determine changes in bladder function after surgery. Secondary aim is to identify predictors of persistence,…
In this study the prevalence and kind of sexual and psychosexual problems will be assessed. Psychological well being is studied as well