94 results
The primary objective of this study is to provide an updated pharmacokinetic profile of orally administered nitrofurantoin in women aged 55 to 75 years.
To determine the clinical value of chronic implantation of an electrode adjacent to the dorsal genital nerve for conditional electrical stimulation in patients with overactive bladder syndrome The aim is to have >60-70% decrease in number of…
To evaluate the efficacy, safety and PK of solifenacin succinate suspension after multiple dose administration.
Evaluation of the effect of pre-TURBT intravesical instillations of MMC mixed with TC-3 Hydrogel on bladder lesion(s) of NMIBC patients.a. Comparison of the effect of pre-TURBT instillations with MMC mixed with TC-3 Hydrogel on bladder lesion(s) to…
To evaluate the efficacy and safety of BOTOX® 100 U compared with placebo in patientswith idiopathic OAB with urinary incontinence whose symptoms have not been adequatelymanaged with anticholinergic therapy.
Main objective: To evaluate the outcomes of the PelFIs in patients with OAB; the relation to the clinical efficacy of antimuscarinic treatment and to hyperactivity of the pelvic floor muscles.Secondary objectives:• To asses the efficacy of…
The primary objective of this trial is to compare the effect of three different doses of ONO-8539 with placebo in the mean change of the number of micturitions per 24 hrs from baseline to 12 weeks.The secondary objectives of this trial will be:*To…
To determine whether rate change is feasible and has a positive influence on the effect of SNS on the symptoms measured with voiding diaries.To investigate whether there are differences between optimal stimulation settings between patients with SNS…
To describe the course of symptoms of BPS/IC after intravesical injection of Botox®.
To determine the therapeutic effect of vardenafil 10 mg taken twice daily (BID) on Overactive Bladder by means of urodynamic measurements (filling cystometry and pressure flow investigations).
To study which technique is most effective to surgically correct a symptomatic cystocele.2. To compare morbidity and post-operative recovery of anterior colporraphy and PerigeeTM.3. To compare the need for repeated pelvic floor surgery following…
To determine the performance (safety and effectiveness) of miniaturo*-I for the treatment of urinary urge incontinence.
The objective of this study is to determine whether bilateral sacral nerve stimulation with FSTLP test is more effective than unilateral stimulation, among patients with non obstructive urinary retention.
The main objective of this study will be to assess whether an additive stimulation of the posterior tibial nerve (PTNS) in combination with bladder training has a significant reduction in frequency of micturition in patients with overactive bladder…
Primary objective: to study the feasibility and toxicity of the combination of intravesical chemotherapy with Mitomycin C and regional 70 MHz microwave therapySecondary objective: to develop a new bladder catheter with sufficient thermocouples to…
Primary Objective: To assess the effect of treatment with three doses of botulinum toxin type-A (Dysport®) versus placebo on the number of episodes of urgency and frequency of micturition experienced in continent female subjects with idiopathic…
This study is designed to demonstrate superiority of efficacy of Propiverine hydrochloride compared to placebo in children suffering from overactive bladder with urinary incontinence.The primary objective is to compare efficacy of Propiverine…
To evaluate the urodynamic effects, the safety and tolerability and the clinical efficacy of AV608 compared with placebo in subjects with idiopathic detrusor overactivity
The objective of the study is to ascertain whether the high effect sizes obtained in the previous studies can be explained according to our working hypothesis, i.e. whether the intervention with Urocell is associated with a structural regeneration…
To evaluate the dose-response relationship of SVT-404776 on efficacy.