13 results
The aim of the current study is to:1. Determine the incidence of CIN after introduction of preventive measures.2. Describe changes in the course of biomarkers serum creatinine, microalbumin and microglobulin related to intravenous ICM administration…
Determinination of the added effects of dietary sodium restriction or diuretic use to antihypertensive and antialbuminuric therapy.
Primary:- Can carboplatin exposure in children be predicted by taking the plasma concentrations of creatinine of cystatine C into account?Secundary:- Which is the effective carboplatin exposure in the current pediatric treatment protocols?- Is there…
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The central hypothesis of this project is that Aliskiren causes a substantial decrease in MSNA in hypertensive patients with CKD.
Methodology (part A):(1) What is the intra-individual variation in refill? (2) Is the magnitude of the ultrafiltration rate of influence on refill? (3) Is the amount of the initial intended blood volume decline of influence on refill? Implementation…
To determine the general usefulness of and a proper moment when blood should be taken for the in vitro IFN-γ assays in patients undergoing chronic haemodialysis.
The primary question is whether certain tubular biomarkers are associated with albuminuria. It is thougt that to much albumin in the pre-urine is toxic to the proximal tubulus. By measuring different kind of damage markers of different locations of…
The primary objective is to investigate if there is an incremental inhibiting effect on MSNA by increasing dosage valsartan above the presently advised dosage. We hypothesize that there will be a further decrease in MSNA as compared to the MSNA…
The primary objective of this study is to determine whether ACE inhibition results in an improvement of microvascular glycocalyx-thickness in patients with type 1 diabetes. The secondary objectives are to investigate whether this (hypothesized)…
To compare the accuracy of the measured GFR using bolus 51Cr-EDTA, and Gd DTPA, and estimated GFR using cystatin C and creatinine with the continuous 125I-labelled iothalamate infusion method.
The purpose of the study is threefold. First, to describe the course of quality of life after renal transplantation and to identify predictors of (un)succesful adjustment. Second, to investigate intra- and interindividual differences that influence…
1. To assess whether nocturnal hemodialysis and renal transplantation give less progression of arterial calcification, compared with conventional hemodialysis and peritoneal dialysis;2. To identify the risk factors for arterial calcification in…