17 results
To evalute the efficacy of rituximab in comparison to continued corticosteroid treatment in ipatients with diopathic nephrotic syndrome unresponsive to 8 weeks of high dose prednisolone.
Collect data in an observational study on outcomes of endovascular fistula creation using the everlinQ endoAVF System
to determine the prevalence and significance of chronic nephrotoxic effects of cisplatin therapy by 1) identifying patients with chronic cisplatin nephrotoxicity and 2) reviewing their QoL. Eventually, this could improve care in these patients
In this single center cohort study the primary objective is to assess minimal residual autoimmunity (MRA) in RTX treated AAV patients. The primary objective is to routinely assess the composition of the memory B-cell and plasma cell compartment…
To examine the effects of mono- and combination therapy with linagliptin and empagliflozine on renal hemodynamics
To investigate whether dietary salt intake influences proximal tubular endocytic function.
The main aims of the present study:1. Define the causality between low immunosuppression, i.e. high IPV, and anti-donor T-cell and B-cells immune responses2. Set a robust benchmark for CRAD3. Improve the knowledge of the biological mechanisms…
The purpose of this study (APPIRED III) is to investigate the efficacy of administered prophylactically RESCAP with regard to the prevention of (severe) renal failure, or renal dysfunction, reducing morbidity and mortality. It also looks at systemic…
To study the renoprotective effect of potassium supplementation in patients with CKD (stage 3b or 4 or estimated glomerular filtration rate [eGFR] 15 - 44 ml/min/1.73 m2).
This study has been transitioned to CTIS with ID 2024-517467-23-00 check the CTIS register for the current data. Primary objective: - To investigate the effect of additional levamisole in comparison with placebo from 4 weeks to 6 months after the…
Main Objective: - Determine feasibility to increase plasma magnesium concentrations in hemodialysis patients by means of increased concentration of magnesium in the dialysate. Secondary Objectives:- Determine safety of increasing plasma magnesium…
Primary: * To assess the change baseline in 24-hr proteinuria with dapagliflozin for six weeks relative to placebo treatment in patients with non-diabetic kidney disease and proteinuria > 500 mg/day on stable ACEi or ARB treatment. Secondary…
To correlate platelet activity, PMV production and platelet and PMV RNA content to renal outcomes in diabetic nephropathy and to investigate the interaction between PMV and glomerular endothelial cells and podocytes.
To compare the antiproteinuric effects of sacubitril/valsartan (ARNI) and valsartan (ARB).
Primary objective is to design a non-invasive, bedside monitoring strategy for early detection of renal graft hypoperfusion after pediatric kidney transplantation, using transabdominal ultrasonography and biomarker surveillance in serum and urine.…
are sildenafil, metformin and simvastatin effective in stimulation of ADH independent urine concentration in man?
Primary objective: to investigate the effect of amiloride on urine volume and urinary concentrating ability in patients on chronic lithium therapy suffering from polyuria.We hypothesize that amiloride therapy will improve urinary concentating…