42 results
to determine if there is an alternative mechanism for urine acidification in men in response to NH4Cl other than that through ENaC
Primary Objective: • To compare urinary concentrating capacity in ADPKD patients with healthy subjects and patient with IgA- or membranous glumerulopathy.Secondary Objectives:• To compare urinary concentrating capacity in ADPKD patients with an eGFR…
To study the extent of impaired urinary concentrating ability in hypothyroidism as well as the pathophysiological mechanisms involved before and after adequate treatment.
The overall aim of this study is to evaluate the use of the thrombin generation test in patients with CKD, including haemodialysis-dependent patients.
The objective of the study is the confirmation or enervation of our hypothesis, i.e. that a situation is present in PD patients with normal peritoneal transport characteristics, whereby diffusion through the peritoneal membrane is retarded by PBR…
to study the effect of everolimus (vs. mycophenolate) on dyslipidemia, ectopic fat accumulation, and cardiovascular function against a common calcineurin inhibitor (CNI) background.
To assess renal sympathetic reinnervation in the kidney allograft by 123-I-MIBG scintigraphy.
The objective of this pilot study is to investigate the association between hemodialysis-associated changes in tryptophan levels and changes in symptoms of depression and fatigue, and the temporal dynamics between depression and fatigue.
zie boven
We try to find a new standard within the field of ''MicroRNA'' proteins, that swim around in peoples blood and/or urine. MicroRNA's are very small proteins, that switches of genes in the cells, they are able to switch genes…
The main objective of this pilot study is to determine the effects of vascular access construction on autonomic and cardiac function.
Primary Objective: -To compare metabolic activity and efficiency directly after transplantation in living and deceased donor kidney grafts. Secondary Objective(s): -To assess whether the contribution of aerobic and anaerobic metabolism differs…
The primary objective is to study the effects of GH substitution therapy in adult GH deficient survivors of childhood cancer. Primary endpoints are organ size, renal function and capillary density of the skin.
With this pilot study we want to see if there are measurable differences in body composition after one year. In what way does the body composition of patients change during the first year after transition from CHD to NHHD or NCHD? Is the weight gain…
This study evaluates glomerular function in children with a solitary functioning kidney. Furthermore anthropometric data is gathered about waist-hip ratio and subscapular skinfold thickness. Anthropometric characteristics can be both a cause as an…
Our primary objective is to investigate the role of connective tissue growth factor (CTGF, a downstream mediator of profibrotic TGF-β1 activity) in peritoneal fibrosis and EPS. We hypothesize that soluble levels of CTGF and CTGF expression in the…
To determine the vitamin K status in children with chronic renal failure (peritoneal dialysis patients, hemodialysis patients) and evaluate whether a correlation between bone and vascular parameters and vitamin K status exists. If vitamin K status…
Phase 1:- The main objective of this phase of the study is to determine the variation of UAC over 8 weeks time in toddlers. - The secondary objective of this phase is to determine the variation of UAC over 3 days time.Phase 2:- The main objective of…
Primary Objective: - to determine cognitive impairment in patients with severe renal failureSecondary Objective(s): - to determine to what extent this impairment improves after a kidney transplantation - to evaluate changes in uremic toxins after…
To study the acute effect of HD on global and regional CBF.