296 results
1. To assess reference values of a pre-defined set of biomarkers for AKI in *surgical* infants with normal kidney function.2. To determine the incidence of AKI in critically ill infants, according to pRIFLE criteria.3. To evaluate the sensitivity…
To study if regular follow-up of PD patients with testing of their theoretical and practical knowledge (hereafter called *new type of follow-up*) can reduce the incidence of peritonitis, reduce the technique failure rate related to peritonitis, and…
To study if there is a role for prophylactic VZV vaccination prior to transplantation to boost the patients B- and T-cell repertoire and thereby reducing the incidence and morbidity associated with herpes zoster.
The main objective of this pilot study is to determine the effects of vascular access construction on autonomic and cardiac function.
Primary Objective: The main objective of this study is to determine whether MRI and ultrasound are capable to distinguish the existence and extent of microcysts in a Dutch population of lithium treated patients.Secondary Objective(s): to determine…
Primary Objective: To calibrate the measurement of ECFV by 125I-iothalamate in subjects with a GFR <60 ml/min and GFR <30 ml/min, using an accepted measurement of ECFV: distribution volume of Bromide.Secondary Objective(s): To…
Objective: To analyze in more detail the complement activation and regulation and especially the functional CFH activity following three types of interventions in patients known with HUS and correlate these to clinical findings. The three…
To evaluate the use of concentration-controlled everolimus, with the reduction or the elimination of tacrolimus, to provide superior renal function and to provide non-inferior rates of the composite efficacy endpoint compared to the tacrolimus…
A 6-month study of efficacy and safety comparing concentration-controlled Certican® with MSCs to Certican® with standard tacrolimus in renal transplant recipients
To determine the value of cystatine-c based renal function assessment in adults with spina bifida when compared to the golden standard of 24-hours urine collection.
To test the efficacy of renal sympathetic denervation therapy with a special focus on preservation of renal allograft function.
Primary objective is to investigate if donor feces infusion is effective in eradication of ESBL producing Enterobacteriaceae in the large intestine. Secondary objective is to determine whether ESBL decolonisation of the large intestine actually…
AKINESIS is a multi-center prospective, uncontrolled clinical study to assess the utility of a plasma NGAL test (Triage® NGAL Test) and a urinary NGAL test (ARCHITECT® Urine NGAL) in predicting worsening renal function in patients presenting with…
The overall aim of the project is to improve health outcomes and autonomy of CKD patients by testing a self-management care model regarding hypertension control. Furthermore, this study will investigate the impeding and facilitating factors for…
Primary Objective: -To compare metabolic activity and efficiency directly after transplantation in living and deceased donor kidney grafts. Secondary Objective(s): -To assess whether the contribution of aerobic and anaerobic metabolism differs…
This study has two main objectives:• to evaluate the prevalence of dRTA in pSS using the urinary acidification test with FF and compare this against the gold standard test with AMCL.• to evaluate whether a low BMD is more prevalent in patients with…
To compare cerebral activity patterns during emotional and cognitive processing among depressed patients with CKD and patients with regular depression.
Primary Objective: Mapping the consequences of a congenital monokidney on kidney function for children with MCKD.Secondary Objective(s): - Giving recommendations about follow-up for children treated with nephrectomy for MCKD.- Defining better blood…
Primary:- to evaluate the pharmacokinetics, in particular the routes and extent of metabolism and excretion, of the study medication after a single oral dose of 1 mg 14C-labeled study medicationSecondary: -to identify the metabolic profile of the…
Primary objective:-To diagnose acute pyelonefritis with MRI in comparison with the reference standard: DMSA scanning.Secondary objectives:- To determine whether MR-diffusion weighted imaging (DWI) has additional value in the imaging of…