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Prevention of recurrent urinary tract infections by multi-drug resistant bacteria, by intravesical administration of gentamicin.

Objective: The main objective is to demonstrate superiority of the intravesical overnight instillation of gentamicin versus oral antibiotic prophylaxis in reducing the number of recurrences of UTI and extending the time-interval to a next UTI, in…

Faecal microbiota transfusion for decolonization of multidrug resistant Enterobacteriaceae in renal transplant recipients (RESET): a pilot study.

Primary Objective: To assess the efficacy and safety of faecal microbiota transfusion in female renal transplant recipients with intestinal carriage of extended-spectrum β-lactamase Enterobacteriaceae (ESBL-E) and/or carbapenemase producing…

The effect of methenamine hippurate to reduce antibiotic prescribing due to new episodes of urinary tract infections (UTI) in elderly women with recurrent UTI- a triple-blinded, randomized placebo-controlled phase IV study

Primary objective: The primary objective of this study is to investigate if taking methenamine hippurate reduce the need for antibiotic usage due to recurrent UTI (measured as the number of courses of antibiotics).Secondary objectives:to investigate…

Gag Therapy for Recurrent urine tract infection Assessing Comparability to International Nitrofurantoin Gold standard study.

The main objective of the study is to compare efficacy between GAG therapy and gold standard treatment (AB prophylaxis) in the prevention of rUTI. Primary questionIs GAG therapy as efficacy as antibiotic prophylaxis in the prevention of rUTI?…

Safety and tolerability of controlled Human Urine Transfusion for Urinary tract infection Prevention (SHUTUP): a pilot study

To investigate the safety and tolerability of controlled human urine transfusion in female patients with recurrent UTI*s.

DUET-trial; DoUble j or External stenting during kidney Transplantation? Study-protocol

Therefore, in the DUET-trial we will investigate whether double J stenting is indeed superior to the use of an external stent in reducing the number of urological complications after kidney transplantation, as measured by the number of PCN…

RUTI-FREEDOM: Recurrent Urinary Tract Infections in Females Receiving Effective Education, Digital Outreach & Management - a multicenter prospective randomized controlled trial in the Netherlands

A pilot study on digital coaching in rUTI at the Urology Department of Isala tested an app-based treatment additional to standard care.[8] The app provides information on rUTI aetiology, lifestyle recommendations, treatments, and the value of…