39 results
The aim of the study is to investigate if alarm treatment in combination with EMDR is a better method for persistent enuresis nocturna than only alarm treatment.Subquestions: 1. What is the success percentage of EMDR with alarm treatment? 2. If EMDR…
The main objective of this study is to assess the additive effect of EMG-feedback in the treatment of LUTS in men.
Objective: Safety and performance of the C-Life Investigational Electrode, and to determine the clinical value for conditional dorsal genital nerve stimulation in patients with overactive bladder syndrome.
To evaluate the mechanism of action of the Vesair Bladder Control System for future product development efforts to improve the System, for marketing efforts in the European Union and to provide data for publications.
Primary Objective: To optimize the dosing regimen of nitrofurantoin in order to enhance the effectivity and the safety of the treatment of cystitis with orally administered nitrofurantoin in patients with suspected or proven cystitis.Secondary…
This study is designed to demonstrate the CV and renal effects of sotagliflozin in patients with T2D, high CV risk, and moderate renal impairment. One of the major objectives of this study is to fulfill the regulatory mandate that any new therapy…
The primary objective of this study is to determine histological ablative efficacy by absence of vital (tumour) cells in the treated prostate zone with (multi)fibre setup in men with PCa scheduled for radical prostatectomy. The secondary objectives…
A non-inferiority/superiority trial was designed for the treatment of uncomplicated cystitis in the Dutch community, in which we compare a 1-day and 3-day regimen of FT to a 5-day regimen of nitrofurantoin to investigate the effect on time to…
The purpose of the INTIBIA pivotal study is to demonstrate the safety and effectiveness of the INTIBIA System in the intended population through 24 months of follow-up. Data at 12-months will be used to support regulatory approval.The objective of…
To evaluate cost effectiviness of the SENS-U (continuous ultrasonic bladder monitoring) in urotherapy for children with functional daytime urinary incontinence.
The main objective of this trial is to determine whether reusable catheters are not less efficient as single use catheters, measured by symptomatic UTIs. Secondary objectives are adverse events like hospital admissions due to UTIs, urethral damage/…
To determine the efficacy of oral fosfomycin in comparison to the standard of care oral ciprofloxacin, in the treatment of FUTI after initial empirical treatment with intravenous antibiotics.To describe the pharmokinetic profile of men treated with…
The primary objective of this study is to prove feasibility and safety of TPLA for LUTS due to BPO in healthy men. The secondary objectives are to determine functional voiding, erectile outcomes and changes on imaging.
Objective: To study the effectiveness of pelvic physical therapy and ES in patients with PD suffering from LUTS. Which are the most effective parameters for ES. Intervention: Intervention: 8 treatment sessions of 30 minutes pelvic physical therapy…
Primary• To assess the safety and tolerability in healthy volunteers of nizaracianine administered IV in three divided dosesSecondary• To perform pharmacokinetic analyses of blood and urine• To determine if bolus injection of nizaracianine enables…
The aim of this study is to evaluate and describe the PK of fosfomycin in individuals receiving oral treatment with multiple dosages of fosfomycin for recurrent and/or complicatedurinary tract infection. The results of this study will be used to…
Target Population:Subjects with urinary incontinence (UI) caused by neurogenic detrusor overactivity (NDO)due to either spinal cord injury (SCI) or multiple sclerosis (MS), who have not beenadequately managed with oral medication and who routinely…
This trial aims to study the effects, costs and cost-effectiveness of an App-based program for women 18 years or older withurinary incontinence (UI) in primary care compared to care delivered by the general practitioner (GP) according to the…
The purpose of this pilot study is to determine the optimal timing to replace a catheter in patients with an indwelling catheter and systematic symptoms of an UTI.