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Pelvic floor muscles in men: an explorative study

We aim to explore the role of PFM activity in male LUTS

POETIC: Point Of carE Testing for urinary tract Infection in primary Care:
Study Stages 3 & 4: Randomised controlled trial and post-RCT observational study

The overall aim of our study is to evaluate the management of suspected uncomplicated UTI in women presenting in primary care through use of a novel point of care test (POCT, Flexicult). This study is being carried out in 4 European networks: Wales…

In Vivo Comparison of Air Charged Catheters with Water Filled Catheters for Intravesical and Intrarectal Pressures Recording during Urodynamic Testing.

Objective: To compare the in vivo pressure responses of air-charged catheters with water filled catheter systems pressure responses during standard cystometry.

Prevalence of overactive bladder (OAB) in patients with pelvic organ prolapse (POP) and predictors of symptoms of OAB after surgical correction of POP.

The primary aim of this research project is to investigate the prevalence and bother of OAB before and after POP repair surgery and to determine changes in bladder function after surgery. Secondary aim is to identify predictors of persistence,…

Digital rectal examination and transabdominal ultrasound as diagnostic tools for constipation. Examination of the rectum in children with urology symptoms

Primary: To investigate if there is a correlation between findings of transabdominal ultrasound measurement of the rectum and rectal digital examination. Secondary: To investigate if there is a correlation between an enlarged rectum (diameter &…

Relevance of Biomarkers and Clinical Predictors of Outcome in Unselected Population with Febrile Urinary Tract Infection at Primary Care and Emergency Department in a Prospective, Randomized Cohort Trial Comparing Short (7 days) Antibiotic Treatment with Conventional Treatment (14 days)

To assess clinical parameters and biomarkers in blood and urine in predicting bacteremia, need for hospital admission, clinical and bacteriologic cure and mortality in patients with fUTI.To determine whether a 7-day duration of antibiotic treatment…

Uremic Toxins, Cardiovascular Effects and Physical Activity in Intensive Hemodialysis

The primary objective of this study is to compare vascular biology (vascular markers and endothelial microparticles) and cardiovascular effects (volume status, blood pressure, pulse wave velocity and microcirculation) in conventional hemodialysis (…

Multicentered randomized controlled trial to test the cost effectiveness of urodynamics in women with symptoms of stress urinary incontinence in whom surgical treatment is considered.

To test the value of preoperatively performed urodynamics with regard to outcome of surgery for stress urinary incontinence (SUI) and to examine whether not performing urodynamics preoperatively is more cost effective than performing urodynamics…

Asymptomatic Bacteriuria and Urinary Tract Infections in pregnant women with and without Diabetes Mellitus

What is the prevalence of ASB and incidence of UTIs during pregnancy in women with DM or GDM compared to pregnant women without diabetes? In addition, risk factors for ASB and UTIs, as well as consequences of ASB and UTIs will be investigated. These…

The central cause of overactive bladder, a pilot study

The objective of this study is to proof the presence of lesions in the brain of patients with overactive bladder and urge-incontinence (OAB wet) as a central cause of this disorder. This survey is a pilot investigation for a larger study on the…

Clinical parameters and biomarkers in blood and urine as predictors for bacteremia, hospital admission, morbidity and outcome in patients with complicated urinary tract infections.
A study in primary care, the medicine emergency room and ICunit.

Establish relevance of a clinical scoring system, and of established and to be identified biomarkers in blood and urine for clinical course and clinical and microbiological outcome of patients with a complicated urinary tract infection, treated in…

Pelvic floor muscle activity as a reaction on emotion, in men with overactive pelvic floor muscles.

The objective of this study is to assess the activity of the pelvic floor muscles during emotion induction, in men with complaints of overactive pelvic floor muscles. The activity is measured during viewing of emotion inducing film excerpts. The…

Alpha-1-microglobulin to diagnose acute pyelonephritis

We want to prove wheter the A1M/creatinine ratio in the urine is a good marker to diagnose an APN, or not. The study design has been made of a prospective observational cohort, controlled by a DMSA-scan.Our aim is to use the A1M/creatinine marker in…

Long-term complications resulting from temporary indwelling urinary catheters in boys. A pilot study.

The aim of this study is to evaluate the: 1) prevalence of structural (urethral strictures) and 2) functional urethral complications (LUTS, abnormal uroflow characteristics and increased post void residual (PVR) volume) in boys post IUC placement.

The influence of sacral neuromodulation on brain areas involved in the sensation of bladder filling in patients with Overactive Bladder (OAB) using fMRI

2.1 Primary Objectives• To identify brain activation evoked by sensation in response to bladder filling in patients with an implanted sacral neurostimulator as a treatment for overactive bladder (OAB), compared to a baseline in OAB patients without…

*The Experience Sampling Method (ESM):
a real-time Patient-Reported Outcome Measure for symptom assessment in patients with overactive bladder syndrome.*

This project will be subdivided into three sections:Part I. Comparison of the ESM vs. SR-BDs and other retrospective questionnaires in the assessment of urological complaints in OAB such as urgency. Part II. Validation of new patient-reported…

Clinical investigation to evaluate the performance and safety of Ambu® aScope* 4 Cysto and aView* Urologia for flexible cystoscopy.

Evaluate the performance of Ambu® aScope* 4 Cysto and aView* Urologia for direct visualization and treatment of the urethra and bladder.Evaluate the patient tolerance to the procedure and the procedural time of Ambu® aScope* 4 Cysto and aView*…

Urinary tract infections in postmenopausal women revisited

The primary objective is to explore the urine microbiome (urobiome) composition of postmenopausal women with and without RUTI at five scheduled time points during one year of follow-up, as well as before, during, and after UTI episodes when they…