41 results
This is a pilotstudy after characterising prostate tissue by using DCE-MRI in patients with a localised prostate cancer.The relation between DCE-MRI and vasculature and oxygenation will be investigated as a preparation for further studies.
To select T cell properties intrinsic to the transplant recipient, which can discriminate between patients who will likely experience acute cellular rejection episodes from those who don*t.
To Assess the Efficacy and Safety of Once-daily Orally Administered ZD4054 10 mg in Non-metastatic Hormone-resistant Prostate Cancer Patients compared to placebo.
The study aims at delivering effective care for older women with urinary incontinence. This condition is underdiagnosed and undertreated, though effective treatments are available to manage urinary incontinence. Therefore, it is important to study…
The objective of the pilot study is to get information on the recruitment of patients, the filling in of the questionnaires, the micturition diary, the course of and information from the interview and about the logistics of the urogynaecological…
The purpose of our study is to assess the subjective stress response during MR guided prostate biopsy and elucidate potential mediating influences of cognitive and affective factors, long term stress exposure and stress-related brain connectivity…
The main objective of this study is to investigate whether access to a peer support platform, age-dependent information provision and games in a smartphone application increases self-reported quality of life, for children receiving a stoma.
The primary objective of this research is external validation of the prediction model that preoperatively estimates the risk of anatomical cystocele recurrence after primary anterior colporrhaphy. The secondary objectives are to identify risk…
This study has been transitioned to CTIS with ID 2024-513521-23-00 check the CTIS register for the current data. All efficacy and safety objectives will compare enzalutamide plus leuprolide and enzalutamide monotherapyversus placebo plus leuprolide.
To examine the impact of a supervised training program on disease-related quality of life and physical fitness in patient with advanced prostate cancer compared to usual care.
To assess the predictive value of early response measurements on PSMA-PET/CT for therapy success, defined as time to development of castration-resistant prostate cancer (CRPC), in order to personalize treatment choice.
To assess the predictive value of early response measurements on PSMA-PET/CT for therapy success, defined as time to development of castration-resistant prostate cancer (CRPC), in order to personalize treatment choice.
We hypothesize that the follow-up and aftercare of prostate cancer in the Netherlands can be led by the GP. We hypothesize that GP-led recurrence detection programme leads to at least equal detection of recurrences as the current follow-up in…
This study has been transitioned to CTIS with ID 2024-514991-41-01 check the CTIS register for the current data. To assess the proportion of UTUC patients with adequate renal function and fit to receive either neo- or adjuvant cisplatin-based…
Investigation of maintenance of erectile function after MR-guided radiotherapy with neurovascular sparing in patients with localized prostate cancer.
To set up a cohort that will serve as a multi-trial platform and facilitate evaluation of new interventional treatment for prostate cancer.
We propose a study to compare the cost-effectiveness of the new UBA to MUS surgery.
Primary Objective: - to investigate health-related quality of life (HRQoL) of patients surviving 2 years or more after the first cycle of an immune checkpoint inhibitor for melanoma or NSCLC.Secondary Objectives:- to assess neurocognitive function,…
Primary objective is to assess the prediction of tumour localisation, extraprostatic extension, metabolism and GS of 7T-MRI for PCa, based on anatomical, functional and metabolic imaging compared to whole-mount histopathology validation after…
To assess non-inferiority of treating patients with localized, intermediate risk prostate cancer in two fractions of 12 Gray (Gy) with a boost to the gross tumor volume of 13.5 Gy per fraction in 8 days, as compared to standard care (36.25 Gy in…