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Pain treatment in renal colics; the role of Instanyl ® in prevention of hospitalization. A Clinical outcomes study.

Main objective: To evaluate the pain reduction in patients receiving Instanyl®Secondary objectives: To evaluate; the duration of pain reduction in patients receiving Instanyl®; the degree of adverse effects in patients receiving Instanyl®: whether…

Cystine Lithiasis in the Netherlands;
Clinical and genetic aspects

- To evaluate the demographic, clinical and genetic characteristics of all known patients with a diagnosis of cystinuria and cystine nephrolithiasis in the Netherlands.- To evaluate the relationship between genotype and phenotype of all known…

"Detection of primary hyperoxaluria in patients with recurrent kidney stones"

Diagnosis of patients with primary hyperoxaluria in a cohort of patients with recurrent urolithiasis.

Percutaneous Nefrolithotomy (PCNL) with MITeC: intraoperative CT-guided evaluation of stone free rate.

The aim of this study is to demonstrate an advantage of intraoperative CT-guided evaluation to ensure that the patient is stone free. If there a still fragments visible they are removed to prevent re-interventions in the future.

Feasibility of CT-guided percutaneous needle puncture for kidneys with CASone system

The aim of this study is to demonstrate the feasibility of CBCT-based stereotactic navigation to perform a better and optimal renal access puncture, which may enable higher stone free rates. This may lower intraoperative ERD during PCNL with…

Effectiveness of drainage of the kidney by percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease caused by uroithiasis.

The primary objective is to assess whether a PCN is non-inferior to double J catheter regarding time to clinical recovery in patients with obstructive kidney disease resulting from urolithiasis.As the secondary objective we would like to investigate…

Dietary oxalate absorption and microbiome diversity in patients with nephrolithiasis and hyperoxaluria: a stable isotope technique.

With this study, we aim to gain insight in the influence of dietary oxalate on urinary oxalate levels by quantification of the intestinal oxalate absorption in patients with recurrent idiopathic calcium oxalate stones, primary hyperoxaluria, and…

Intra-operative cone-beam computed tomography for detecting residual stones in percutaneous nephrolithotomy, a randomized controlled trial

Determining the added value of cone-beam computed tomography in percutaneous nephrolithotomy, by measuring differences in the stone-free rates for patients with cases in which a cone-beam CT-scanner is used versus patients with cases in which no…

Plasma oxalic acid level, renal oxalate deposition and renal transplant function

Primary Objective: * Study the relationship between the pre-transplant plasma oxalic acid level and the risk of oxalate deposition in for cause renal transplant biopsies within 6 months after renal transplantation. Secondary Objective(s): * Track…

Assessment of endogenous oxalate production and investigation of glyoxylate/oxalate pathways in primary hyperoxaluria patients and healthy subjects

Primary: Quantification of oxalate and glycine production in both healthy subjects and PH patients in order to obtain reference values for clinical trials.Secondary: To obtain more insight in the glyoxylate/oxalate pathway, and in particular the…