368 results
• To evaluate the safety of up to 3 additional courses of oral QLT091001 administered once daily for 7 days in subjects with LCA or RP caused by RPE65 or LRAT gene mutations who have been treated previously with a single 7-day course of QLT091001 in…
Objective: To investigate whether binocular patching in combination with posture adherence is superior to posture adherence alone in achieving visualization of the superior fundus quadrants or not.
Primary: To explore the diagnostic value to distinguish PAF and MSA of a variety of tests: corneal confocal microscopy optical coherence tomography (OCT) to measure the retinal nerve fibre layer thickness and total macular volume, corneal…
The primary objective is to obtain OCT data for children aged 4 to 10 diagnosed with non-syndromic craniosynostosis and to compare these to the normal reference values.
The primary objective of this study is to determine the Optical Density Ratio (ODR) for the prototype CORIMAP camera and compare the ODR values with the Oxymap T1 mounted on a regular fundus camera in a healthy adult population. For comparison, it…
PROUD is a multicentre prospective study, using clinical factors in combination with additional tests with the aim to clarify more about the aetiology and pathogenesis of MS.
To explore and optimize the usability of Doppler-OCT scanning of conditions affecting any of the retino-choroidal layers.
To simplify the operational technique for the eye surgeon. To minimize the risk of complications which occur occasionally with the standard technique, such as glaucoma and cataract. In addition, the surgery is less burdensome to the patient since…
To further optimize 7.0 Tesla MRI techniques and to develop new MRI techniques that will enable state-of-the-art clinical and cognitive research leading to improved patient care. Whereas some applications of 7.0 Tesla MRI already show improvements…
The objective of this investigation is to describe visual outcomes and assess the safety at 12 months (330 - 420 days) post bilateral implantation of the AcrySof® IQ PanOptix* Presbyopia correcting IOL Model TFNT00.
To identify parameters that may *announce* or even predict an upcoming allograft rejection after DMEK using routine ophthalmic diagnostic devices.
2.1 Primary objectives2.1.1 Cross-sectional part• Technical evaluation of the functional and structural outcome measures to support a biomarker qualification by regulatory authorities and payers. 2.1.2 Longitudinal part • Assessment of prognostic…
The primary objective is to study glaucomatous structural brain changes in a longitudinal manner, and how it relates to visual functional loss and glaucomatous retinal changes over time.
To obtain and evaluate OCT-probe recordings and to test the interaction between the OCT-probe and the robot.
Development of a method and diagnostic instrumentation for characterizing the peripheral ocular characteristics of normal subjects (with healthy eyes) in a clinical setting.Primary objective of the study: To measure the distribution of the ocular…
Dissection of etiology of myopia- identification of genetic risk factors- identification of environmental risk factors- evaluation of the long term safety of Artisan phakic intraocular lenses for the correction of high degree myopia
Primary Objective: to derive iPSCs from patients with a variety of diseases caused by genetic mutations or genetic predisposition to disease or of unknown origin. The cells will be propagated and differentiated into a variety of somatic cell types…
To visualize the different components of RAP lesions with high resolution Doppler OCT, and to evaluate the change in intra- and transretinal flow after treatment.
To document mean and range of straylight values in patients with anterior segment disorders possibly under several visual angles
The main objective is to describe the interactions between physical sensory stimulations and high-level prior assumptions that give rise to visual perception. In two secondary objectives, we will advance novel model-based neuroimaging data-analysis…