108 results
The primary objective is to obtain OCT data for children aged 4 to 10 diagnosed with non-syndromic craniosynostosis and to compare these to the normal reference values.
To explore and optimize the usability of Doppler-OCT scanning of conditions affecting any of the retino-choroidal layers.
The objective of this study is to evaluate the effect of different preventive strategies on the occurrence of macular edema after cataract surgery in non-diabetic and diabetic patients.
To detect ophthalmic differences between patients and controles. To detect (early) changes in the retina in (pre)symptomatic RVCL disease carriers, in order to find a *biomarker* for disease stage and progression.
To visualize the different components of RAP lesions with high resolution Doppler OCT, and to evaluate the change in intra- and transretinal flow after treatment.
The primary objective of this study is to determine the Optical Density Ratio (ODR) for the prototype CORIMAP camera and compare the ODR values with the Oxymap T1 mounted on a regular fundus camera in a healthy adult population. For comparison, it…
Primary: to compare the treatment effect of ranibizumab PRN (visual acuity loss and/or SD-OCT disease activity guided retreatment) versus aflibercept bimonthly regimen on central retinal thickness stability as measured by mean fluctuations between…
2.1 Primary objectives2.1.1 Cross-sectional part• Technical evaluation of the functional and structural outcome measures to support a biomarker qualification by regulatory authorities and payers. 2.1.2 Longitudinal part • Assessment of prognostic…
To obtain and evaluate OCT-probe recordings and to test the interaction between the OCT-probe and the robot.
Are changes in cognitive functioning related to structural changes in the brain in patients with type 1 diabetes mellitus. How are these changes related to diabetic complications like duration of chronic hypoglycaemia, disease duration and presence…
Primary objective:To demonstrate that an individualized stabilization-criteria-driven PRN dosingregimen (PRN) with 0.5-mg ranibizumab administered with or without adjunctive lasertreatment has superior efficacy as compared to the current standard of…
Assess the quality and applicability of smartphone assisted and handheld fundus photography, compared to standard fundus photography. Photographs will be taken in non-mydratic and mydriatic conditions.
Identification of the proteins that are involved in neurite outgrowth in PDR. We want to determine what protein levels are increased in the vitreous by local production and which RNA transcripts are present in the fibrotic membranes of patients with…
Both RCTs and long-term follow-up studies are required to establish optimal fetal management and provide clinicians a better understanding of the impact of these early interventions on child development in order to improve the quality of antenatal…
Primary ObjectiveTo investigate whether half-dose PDT treatment leads to a higher percentage of chronic CSC patients with subretinal fluid on OCT achieving an absence of this subretinal fluid on OCT as compared to HSML treatment.Secondary…
The objective of this study is to establish normative data on OCT in children between the ages of 4 to 10.
To detect ophthalmic differences between patients and controles. To detect (early) changes in the retina in (pre)symptomatic HCHWA-D disease carriers, in order to find a *biomarker* for disease stage and progression.
Primary objectives:- To investigate the long-term outcome after successful treatment (no subretinal fluid on OCT) in the PLACE trial.- To investigate whether a cross-over treatment of half-dose PDT to HSML in cCSC patients who either did not respond…
The objective of the study is to map in a standardized way the phenotype of carriers with known LHON mutations. We want to study the natural course of persons with LHON mutations by examining patients several times. Further, we want to study a…
The objective of this study is to observe the anatomical and functional outcomes of ocriplasmin over a 6-month follow-up period.