58 results
The primary objective is to obtain OCT data for children aged 4 to 10 diagnosed with non-syndromic craniosynostosis and to compare these to the normal reference values.
To explore and optimize the usability of Doppler-OCT scanning of conditions affecting any of the retino-choroidal layers.
To detect ophthalmic differences between patients and controles. To detect (early) changes in the retina in (pre)symptomatic RVCL disease carriers, in order to find a *biomarker* for disease stage and progression.
To visualize the different components of RAP lesions with high resolution Doppler OCT, and to evaluate the change in intra- and transretinal flow after treatment.
The primary objective of this study is to determine the Optical Density Ratio (ODR) for the prototype CORIMAP camera and compare the ODR values with the Oxymap T1 mounted on a regular fundus camera in a healthy adult population. For comparison, it…
Are changes in cognitive functioning related to structural changes in the brain in patients with type 1 diabetes mellitus. How are these changes related to diabetic complications like duration of chronic hypoglycaemia, disease duration and presence…
Assess the quality and applicability of smartphone assisted and handheld fundus photography, compared to standard fundus photography. Photographs will be taken in non-mydratic and mydriatic conditions.
Identification of the proteins that are involved in neurite outgrowth in PDR. We want to determine what protein levels are increased in the vitreous by local production and which RNA transcripts are present in the fibrotic membranes of patients with…
Both RCTs and long-term follow-up studies are required to establish optimal fetal management and provide clinicians a better understanding of the impact of these early interventions on child development in order to improve the quality of antenatal…
To detect ophthalmic differences between patients and controles. To detect (early) changes in the retina in (pre)symptomatic HCHWA-D disease carriers, in order to find a *biomarker* for disease stage and progression.
The objective of the study is to map in a standardized way the phenotype of carriers with known LHON mutations. We want to study the natural course of persons with LHON mutations by examining patients several times. Further, we want to study a…
To confirm the previously reported negative predictive value of urine NTproBNP for ROP in large, multi center cohort of preterm infants.
1. To determine if zinc supplementation in AMD patients has a direct measurable effect on the complement system explaining the mechanism through which this substance exerts its influence on AMD progression.2. To determine whether this proposed…
The aim of this study is to investigate whether the risk and severityof retinal detachment are related to skin autofluorescence (AF).
This study has the following goals: 1. Generation of normative values for full-field ERGs within single recording sessions according to ISCEV standard.2. To compare function (results of full-field ERG) with anatomy (retinal thickness on OCT) in…
Objective: To investigate whether binocular patching in combination with posture adherence is superior to posture adherence alone in achieving visualization of the superior fundus quadrants or not.
The aim of this study is to investigate whether skin autofluorescence (AF) is predictive of postoperative PVR (and corresponding surgical failure) in patients being surgically treated for retinal detachment and to investigate some pathways which may…
The aim of this study is to determine if retinal defects and detachments can be detected by fundus photographs taken with the Optos 200Tx fundus camera.
Assess correlation between CFH polymorphism and the effect of laser treatment of drusen.
To perform an external (geographic and temporal) validation of predictive models for estimating the probability of PVR following primary RD using a subgroup of SNPs from a total of 197 in 30 candidate genes previously studied.