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Optical coherence tomography in non-syndromic craniosynostosis patients

The primary objective is to obtain OCT data for children aged 4 to 10 diagnosed with non-syndromic craniosynostosis and to compare these to the normal reference values.

The exploratory use of an experimental flow-OCT instrument in chorioretinal diseases

To explore and optimize the usability of Doppler-OCT scanning of conditions affecting any of the retino-choroidal layers.

*The CORIMAP study - A comparison study between a prototype retinal handheld oximeter (CORIMAP camera) and the Oxymap T1*

The primary objective of this study is to determine the Optical Density Ratio (ODR) for the prototype CORIMAP camera and compare the ODR values with the Oxymap T1 mounted on a regular fundus camera in a healthy adult population. For comparison, it…

E-mental health intervention for patients with exudative retinal diseases who receive intraocular anti-VEGF injections (E-PsEYE) - pilot study

To investigate if E-PsEYE leads to a reduction in depression and anxiety symptoms (primary outcomes) and problems with adaptation to vision loss(secondary outcome). Conducting a process evaluation to determine adherence and patient satisfaction. To…

Study on half-dose Photodynamic therapy versus Eplerenone in chronic CenTRAl serous chorioretinopathy (SPECTRA trial)

Primary Objective: to investigate whether half-dose PDT treatment leads to a higher percentage of cCSC patients with SRF on OCT at baseline, achieving an absence of this SRF on OCT as compared to eplerenone treatment.Secondary Objectives: to…

A Randomised, Open Label, Outcomes-Assessor Masked, Prospective, Parallel Controlled Group, Phase 3 Clinical Trial Of Retinal Gene Therapy For Choroideremia Using An Adeno-Associated Viral Vector (AAV2) Encoding Rab Escort Protein 1 (REP1)

The objective of the study is to evaluate the efficacy and safety of a single sub-retinal injection of AAV2-REP1 in subjects with choroideremia (CHM).

Determinants of Ectopic Calcification in Pseudoxanthoma Elasticum and Healthy controls:
Evaluation of their Relations

The main objective of this study is to compare calcification promoting and inhibiting factors and their interactions in the serum of PXE patients and healthy controls. Secondary objectives (optional) are:1) to identify differences in cognitive…