85 results
The primary objective of the current study is to investigate the effectiveness of MCP-ED in a clinical sample of adolescents with an ED. As a result, this study will provide critical information about the potential relevance of implementing MCP-ED…
We aim to investigate the relationship between positive schema activation and subsequent tests of emotional schema memory, and whether tDSC during positive schema activation can facilitate retrieval of emotional memory for positive information in…
This study has been transitioned to CTIS with ID 2024-517636-22-00 check the CTIS register for the current data. The main objective of the present study is to investigate the association between in vivo regional synaptic loss ([18F]SynVesT-1 PET),…
This study is aimed at investigating the effect of imagery rescripting on selfreported low self-esteem in personality disorders and the effect on diverse complaints (anxiety, depression), wellbeing and core cognitions. This might be a step into…
The primary objective is to investigate if the stress-induced dynamics across stress systems are impaired in patients with CT-related depression compared to non-CT-related depression and healthy controls. The secondary objective is to examine how…
Objective of the quantitative and qualitative study:To gain knowledge about which transdiagnostic factors are associated with dropout from and outcome of intensive high-specialty treatment.Objective of the pilot study:To gain insight into the role…
The aim is to determine whether individuals with anxiety-related disorders experience faster functional recovery with BI-CBT compared to weekly CBT. If so, a broader range of treatments, decision support, and a detailed implementation plan will be…
The objective of this study is, to detect potential uses of plasma biomarkers in primary care, by (a) To investigate if plasma biomarkers are associated with working diagnosis in primary care.(b) To ascertain if diagnosis and patient management…
Hypothesis: 5 day multi daily neuronavigated Theta burst sessions (developed by Stanford University and coined, SNT, i.e. Stanford NeuromdulaTion protocol) are more (cost-) effective than standard 10 Hz rTMS in patients with treatment resistant…
The primary objective is to explore phenotypes of (sub)clinical PMDD and explore the impact of (sub)clinical PMDD on the lives of the affected women.The secondary objective is to assess the validity of a Dutch translation of the self-administered C-…
To study the effectiveness and exploratively the presumed working mechanisms of the new MBT-early intervention. Given that MBT-early specifically targets young people with early characteristics of borderline personality disorder, we expect to find…
The objective of the Happy Friends, Positive Minds Cluster Randomized Controlled Trial is to evaluate the effectiveness of Happy Friends, Positive Minds prevention program, delivered by experienced mindfulness health professionals, on self- and…
This study has been transitioned to CTIS with ID 2024-517805-10-01 check the CTIS register for the current data. We aim to investigate whether sodium oxybate can be used as a novel treatment in psychiatric patients with catatonia. Our primary…
The primary objective is to study the effectiveness of EMDR in comparison to PE for treating military personnel and veterans with psychological trauma. Secondary objectives are:1. to investigate if working memory capacity is a predictor of EMDR…
We aim to investigate in an RCT the (cost-)effectiveness of CM, compared with usual care CBT in the treatment of CUD in youths aged 16 to 22 years. Both outpatient treatments are provided for 12 weeks.PRIMARY STUDY QUESTION:1. What is the efficacy…
Primary Objective:Our primary goal is to investigate the feasibility of a large pragmatic study of the effectiveness of a tailored MLI for patients with depression in general practice and to evaluate potential barriers and facilitators in a process…
The primary aim of this study is to investigate the feasibility, acceptability and user-friendliness of implementing PM+ in Dutch prisons. This is a version of PM+ that is specifically adapted to the prisoner population and prison context. The…
The main objective of this study is to investigate whether there are differences in the way factors such as learning progress (LP) maximization and prediction error (PE) minimization drive the exploratory behavior of children with autism compared to…
To evaluate whether cue-induced nicotine craving and cognitive control in smoking individuals can be modulated with cTBS at left or right insula using deep TMS.
1. To examine whether there is an increase in (nigro)striatal dopaminergic functioning in individuals of West-African descent relative to those of Dutch descent (assessed in older participants with DAT SPECT and with NM-MRI in the entire sample). (…