34 results
Primary aim:In recently traumatized individuals (at the latest on day ten post trauma exposure) with a high initial level of distress, we aim to assess the effectiveness of intranasal OT in preventing symptoms of PTSD at one months post intervention…
The aim of this research project is to investigate cannabidiol as a new medicine to target the cannabinoid system in the reduction of anxiety disorder symptoms. The research question is whether cannabidiol, as an augmentation strategy of exposure…
To investigate the efficacy of testosterone enhanced exposure therapy for social anxiety disorder.
Primary objectives: 1. To translate and adapt the iCBT program TELLUS for use in IFRC humanitarian aid workers2. To determine feasibility of TELLUS in terms of: completion rates and self-reported treatment credibility/ expectancySecondary objective:…
a. By this research a treatment protocol for NET will be quantitatively and qualitatively evaluated on its effects. b. With the research findings it is possible to identify subgroups within the research population and indicate who benefits most from…
In this functional Magnetic Resonance Imaging (fMRI) study, the primary objective is to examine the acute effects of intranasal OT administration on emotional- and reward-related brain processes in PTSD patients compared to traumatized healthy…
The main objective of this study is to assess the efficiency of oxytocin compared to placebo as an addition to the exposure sessions in the treatment of PTSD. We hypothesize that adding oxytocin to exposure in TF-CBT produces acute changes in…
The first objective of this study is whether DCS addition to exposure therapy enhances symptom reduction in PD+AGO. The second objective of the study is to establish the optimal timing of administration of D-cycloserine (directly pre- or post…
To evaluate the effect on sleep and ptsd of the drug Doxazosin Retard in patients with PTSD who also have sleep problems.
The first aim of the study is to investigate whether DCS addition to exposure therapy enhances symptom reduction in PD+AGO. The second objective of the study is to establish the optimal timing of administration of DCS (30 minutes before or directly…
The main objective of the study is to determine whether, and if so, to what extent, there are differences in memory vividness, detail and certainty between OCD patients, another anxiety disorder patients and healthy subjects in a repetitive checking…
To determine the efficacy and safety of memantine for patients with OCD.
The aim of this pilot-study is to establish the potential efficacy of acute doses of 50 mgs D-cycloserine (DCS), a partial NMDA agonist, in accelerating and/or augmenting the effect of exposure and response prevention (ERP) in the treatment of…
The objective is to investigate wether a brief CBT with parental involvement among children and adolescents with ASD reduces the risk of PTSD compared to a waitlist control group.
The aim of the present study is to examine whether the positive interpretive training has an therapeutic effect in patients with an anxiety disorder.
The objective of this study is to improve the prognosis of patients with the Obsessive Compulsive Disorder (OCD), with poor insight. A psychological treatment, the Inference Based Approach (IBA), which is developped and has been proven effective in…
This study aims to evaluate the safety, tolerability and sedative proporties of a single dose of intransally administered dexmedetomidine in person odler than 65 years, differentiating between person using beta-blocking medication and those not…
To demonstrate non-inferiority of conscious sedation with intranasal dexmedetomidine for performing dental care in patients with intellectual disability and dentophobia.
This study has been transitioned to CTIS with ID 2024-516427-13-00 check the CTIS register for the current data. Substudy A: The primary objective will be to investigate the relationships between HPA axis dysfunction, early life adversity (ELA), and…
The first goal of the current research is to investigate whether EMDR prior to CBT, compared to an active psychological control condition (*supportive counseling*), improves treatment tolerability, adherence, and effectiveness. The second goal is to…